
CAS Number7647-17-8
SynonymsEINECS 231-600-2; cesium,chloride; MFCD00010955; Cesium chloride
Molecular FormulaCsCl
Molecular Weight168.36
Purity99.9%
Density3.983
Boiling Point1290 °C
Melting Point645 °C (lit.)
Appearancecrystals, chunks or beads
EINECS231-600-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 7647-17-8 |
| Catalog No. | 2A-9009702 |
| Chinese Name | 氯化铯 |
| Synonyms | EINECS 231-600-2; cesium,chloride; MFCD00010955; Cesium chloride |
| Molecular Formula | CsCl |
| Molecular Weight | 168.36 |
| Purity | 99.9 |
| Density | 3.983 |
| Boiling Point | 1290 °C |
| Melting Point | 645 °C (lit.) |
| Appearance | crystals, chunks or beads |
| Water Solubility | 1860 g/L (20 ºC) |
| Storage Condition | The warehouse is ventilated and dry at low tempera |
| Application | Cesium chloride is a blocker of potassium channels. Cesium chloride prevents the reduction in sodium ion transport produced by alloxan [1][2]. Cesium chloride has induced cardiac arrhythmias, includin |
| EINECS | 231-600-2 |
| HTC | 28273980 |
| PubChem ID | 329753296 |
| MDL Number | MFCD00010955 |
| SMILES | [Cl-].[Cs+] |
| InChI | 1S/ClH.Cs/h1H;/q;+1/p-1 |
| InChI Key | AIYUHDOJVYHVIT-UHFFFAOYSA-M |
| NACRES Code | NA.55 |
| UNSPSC | 12352302 |
| Hazard Symbols | Transport |
| MSDS | msds/9702_1_7647_17_8.pdf |
| Bioactivity | Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel In Vitro Cesium chloride (CsCl) decreases the increment of membrane potential, the elevation of intracellular calcium and the upregulation of NOS, ET-1 and VEGF expressions, which are induced by Acrolein[3]. In Vivo Cesium Chloride (12 mg/100 g body weight, daily for 30 days; i.p.; male Wistar rats- BOO model) could significantly weaken the effect of XJT (traditional Chinese medicine) on not only the expression of these potassium channels but also the bladder weight, urodynamics, and oxidative stress[1]. References [1]. Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258. [2]. Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130(1):19-27. [3]. Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46(12):1437-1445. [4]. O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28(8):1059-1065. Chemical & Physical Properties Density 3.983 Boiling Point 1290 °C Melting Point 645 °C(lit.) Molecular Formula CsCl Molecular Weight 168.359 Flash Point 1303°C Exact Mass 167.874298 Index of Refraction 1.6418 InChIKey AIYUHDOJVYHVIT-UHFFFAOYSA-M SMILES [Cl-].[Cs+] Stability Stable. Deliquescent. Incompatible with strong oxidizing agents, strong acids. Protect from moisture. Water Solubility 1860 g/L (20 ºC) |
| Use of | Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3]. Properties Articles78 Name caesium chloride Synonym More Synonyms Cesium chloride Biological Activity Description Cesium chloride is a blocker of potassium channel. Cesium chloride prevents the decrease of Na+ transport produced by Alloxan[1][2]. Cesium chloride has induced cardiac arrhythmias, including torsade de pointes in animal models[3]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel In Vitro Cesium chloride (CsCl) decreases the increment of membrane potential, the elevation of intracellular calcium and the upregulation of NOS, ET-1 and VEGF expressions, which are induced by Acrolein[3]. References [1]. Sun J, Shen W, et al. A Chinese Medicine Formula "Xian-Jia-Tang" for Treating Bladder Outlet Obstruction by Improving Urodynamics and Inhibiting Oxidative Stress through Potassium Channels. Evid Based Complement Alternat Med. 2017;2017:8147258. [2]. Soto C, et al. Alloxan decreases intracellular potassium content of the isolated frog skin epithelium. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130(1):19-27. [3]. Ouyang JS, Li YP, Li CY, et al. Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. Free Radic Res. 2012;46(12):1437-1445. [4]. O'Brien CE, et al. Cesium-induced QT-interval prolongation in an adolescent. Pharmacotherapy. 2008;28(8):1059-1065. Chemical & Physical Properties Molecular Formula CsCl Exact Mass 167.874298 Index of Refraction 1.6418 InChIKey AIYUHDOJVYHVIT-UHFFFAOYSA-M SMILES [Cl-].[Cs+] Stability Stable. Deliquescent. Incompatible with strong oxidizing agents, strong acids. Protect from moisture. |
| Transport Info | Product name: Purity: 99.99% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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