CAS Number62893-20-3
SynonymsCefoperazone sodium; MFCD07793331; cefoperazone-Na; Sodium cefoperazone; cefoperazone monosodium; EINECS 263-751-5; Tomabef; cephoperazone sodium; Cefoperazone sodium [USAN:JAN]; Cefoperazone sodium salt; CEFOBID IN PLASTIC CONTAINER; T 1551; Cefoperazonesodium; Cefoperazone (sodium salt)
Molecular FormulaC25H26N9NaO8S2
Molecular Weight667.65
Purity870-1015 μg/mg (anhydrous basis)%
Melting Point200-202°C
Appearancepowder or crystals
EINECS263-751-5
Symbol
Signal WordWarning
Please Login or Create an Account to: See VlP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 62893-20-3 |
| Catalog No. | 2A-9009649 |
| Chinese Name | 头孢哌酮钠 |
| Synonyms | Cefoperazone sodium; MFCD07793331; cefoperazone-Na; Sodium cefoperazone; cefoperazone monosodium; EINECS 263-751-5; Tomabef; cephoperazone sodium; Cefoperazone sodium [USAN:JAN]; Cefoperazone sodium salt; CEFOBID IN PLASTIC CONTAINER; T 1551; Cefoperazonesodium; Cefoperazone (sodium salt) |
| Molecular Formula | C25H26N9NaO8S2 |
| Molecular Weight | 667.65 |
| Purity | 870-1015 μg/mg (anhydrous basis) |
| Melting Point | 200-202°C |
| Appearance | powder or crystals |
| Water Solubility | H2O: 50 mg/mL, clear, faintly yellow |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | Cefoperazone sodium salt is a cephalosporin antibiotic that inhibits rMrp2-regulated [3H]E217βG uptake with an IC50 of 199 μM. |
| EINECS | 263-751-5 |
| HTC | 2941905600 |
| PubChem ID | 24892686 |
| MDL Number | MFCD07793331 |
| SMILES | [Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C([O-])=O)c5ccc(O)cc5)C(=O)C1=O |
| InChI | 1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2;/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41);/q;+1/p-1/t15-,16-,22-;/m1./s1 |
| InChI Key | NCFTXMQPRQZFMZ-WERGMSTESA-M |
| Beilstein/REAXYS | 4902135 |
| NACRES Code | NA.85 |
| UNSPSC | 51102829 |
| Hazard Symbols | Transport |
| MSDS | msds/9649_1_62893_20_3.pdf |
| Bioactivity | Cefoperazone sodium salt is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.Target: AntibacterialCefoperazone is a sterile, semisynthetic, broad-spectrum, parenteral cephalosporin antibiotic for intravenous or intramuscular administration. After intravenous administration of 2 g of Cefoperazone, levels in serum rang from 202μg/mL to 375 μg/mL depending on the period of drug administration. After intramuscular injection of 2 g of Cefoperazone, the mean peak serum level is 111 μg/mL at 1.5 hours. At 12 hours after dosing, mean serum levels are still 2 to 4 μg/mL. Cefoperazone is 90% bound to serum proteins. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Kato, Y., et al., Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of beta-lactam antibiotics. Drug Metab Dispos, 2008. 36(6): p. 1088-96. [2]. Craig, W.A. and A.U. Gerber, Pharmacokinetics of cefoperazone: a review. Drugs, 1981. 22 Suppl 1: p. 35-45. Chemical & Physical Properties Melting Point 200-202°C Molecular Formula C25H26N9NaO8S2 Molecular Weight 667.649 Exact Mass 667.124329 PSA 273.69000 InChIKey NCFTXMQPRQZFMZ-WERGMSTESA-M SMILES CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C(C(=O)[O-])=C(CSc4nnnn4C)CSC23)c2ccc(O)cc2)C(=O)C1=O.[Na+] Water Solubility H2O: 50 mg/mL, clear, faintly yellow |
| Use of | Properties Articles30 Name sodium,(6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Synonym More Synonyms Cefoperazone sodium Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Kato, Y., et al., Involvement of multidrug resistance-associated protein 2 (Abcc2) in molecular weight-dependent biliary excretion of beta-lactam antibiotics. Drug Metab Dispos, 2008. 36(6): p. 1088-96. [2]. Craig, W.A. and A.U. Gerber, Pharmacokinetics of cefoperazone: a review. Drugs, 1981. 22 Suppl 1: p. 35-45. Chemical & Physical Properties Molecular Formula C25H26N9NaO8S2 Exact Mass 667.124329 PSA 273.69000 InChIKey NCFTXMQPRQZFMZ-WERGMSTESA-M |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Cefodizime | 69739-16-8 | 2A-9009644 |
| Cefodizime sodium | 86329-79-5 | 2A-9009645 |
| Cefonicid | 61270-58-4 | 2A-9009646 |
| Cefonicid sodium | 61270-78-8 | 2A-9009647 |
| Cefoperazone acid | 62893-19-0 | 2A-9009648 |
| Cefotetan; Cefotetan sodium | 69712-56-7 | 2A-9009653 |
| Cefotiam | 66309-69-1 | 2A-9009655 |
| Cefoxitin | 35607-66-0 | 2A-9009656 |
| Cefoxitin sodium | 33564-30-6 | 2A-9009657 |
| Cefozopran | 113359-04-9 | 2A-9009658 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS