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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > L-METHIONINE SULFOXIMINE
L-METHIONINE SULFOXIMINE structure, CAS 15985-39-4

L-METHIONINE SULFOXIMINE

CAS Number15985-39-4

SynonymsL-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine; 2-Amino-4-(S-methylsulfonimidoyl)butanoic acid; MFCD00002621; UNII:M9P6YZ6JX9; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic acid; L-Methionine sulfoximine

Molecular FormulaCH3S(O)(=NH)CH2CH2CH(NH2)CO2H

Molecular Weight180.23

Purity98.00%

Density1.5±0.1 g/cm3

Boiling Point352.2±52.0 °C at 760 mmHg

Melting Point>210ºC (dec.)(lit.)

Flash Point

AppearanceWhite crystalline powder

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Cat. No.: 2A-9093952 Purity: 98.00%
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Quality Control of [ 15985-39-4 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number15985-39-4
Catalog No.2A-9093952
Chinese NameL-蛋氨酸磺酸盐
SynonymsL-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine; 2-Amino-4-(S-methylsulfonimidoyl)butanoic acid; MFCD00002621; UNII:M9P6YZ6JX9; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic acid; L-Methionine sulfoximine
Molecular FormulaCH3S(O)(=NH)CH2CH2CH(NH2)CO2H
Molecular Weight180.23
Purity98.00
Density1.5±0.1 g/cm3
Boiling Point352.2±52.0 °C at 760 mmHg
Melting Point>210ºC (dec.)(lit.)
AppearanceWhite crystalline powder
Storage Condition0-6°C
ApplicationL-methionine-DL-sulfoxide oxime (MSX) is an inhibitor of glutamine synthetase. L-methionine-DL-sulfoxide oxime is also a potent convulsant and mainly affects the metabolism and morphology of astrocyte
HTC2925290090
PubChem ID329769992
SMILESCS(=N)(=O)CCC(N)C(=O)O
InChIInChI=1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1
InChI KeySXTAYKAGBXMACB-DPVSGNNYSA-N
Hazard Symbolstransportation
BioactivityL-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia. Related Catalog Research Areas >> Neurological Disease References [1]. Albrecht J, Norenberg MD. L-methionine-DL-sulfoximine induces massive efflux of glutamine from cortical astrocytes in primary culture. Eur J Pharmacol. 1990;182(3):587-589. [2]. Premakumar R, Sorger GJ, Gooden D. Repression of nitrate reductase in Neurospora studied by using L-methionine-DL-sulfoximine and glutamine auxotroph gln-1b. J Bacteriol. 1980;143(1):411-415. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 352.2±52.0 °C at 760 mmHg Melting Point >210ºC (dec.)(lit.) Molecular Formula C5H12N2O3S Molecular Weight 180.225 Flash Point 166.8±30.7 °C Exact Mass 180.056870 PSA 112.62000 LogP -1.38 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.560 InChIKey SXTAYKAGBXMACB-DPVSGNNYSA-N SMILES CS(=N)(=O)CCC(N)C(=O)O Storage condition 0-6°C Stability Temperature Sensitive
Use ofL-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia. Properties Articles20 Name L-methionine sulfoximine Synonym More Synonyms L-Methionine-DL-sulfoximine Biological Activity Description L-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia. Related Catalog Research Areas >> Neurological Disease References [1]. Albrecht J, Norenberg MD. L-methionine-DL-sulfoximine induces massive efflux of glutamine from cortical astrocytes in primary culture. Eur J Pharmacol. 1990;182(3):587-589. [2]. Premakumar R, Sorger GJ, Gooden D. Repression of nitrate reductase in Neurospora studied by using L-methionine-DL-sulfoximine and glutamine auxotroph gln-1b. J Bacteriol. 1980;143(1):411-415. Chemical & Physical Properties Molecular Formula C5H12N2O3S Exact Mass 180.056870 PSA 112.62000 LogP -1.38 Index of Refraction 1.560 InChIKey SXTAYKAGBXMACB-DPVSGNNYSA-N SMILES CS(=N)(=O)CCC(N)C(=O)O Stability Temperature Sensitive
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Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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