EN
0
Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide structure, CAS 1776112-90-3

N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide

CAS Number1776112-90-3

SynonymsMFCD29079007; YXX2180047; Mavelertinib; UNII:YXX2180047

Molecular FormulaC18H22O2N9F1

Molecular Weight415.43

Purity98.00%

Density1.5±0.1 g/cm3

Boiling Point

Melting Point

Flash Point

Appearance

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9093743 Purity: 98.00%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 1776112-90-3 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1776112-90-3
Catalog No.2A-9093743
Chinese NameMavelertinib
SynonymsMFCD29079007; YXX2180047; Mavelertinib; UNII:YXX2180047
Molecular FormulaC18H22O2N9F1
Molecular Weight415.43
Purity98.00
Density1.5±0.1 g/cm3
ApplicationMavelertinib is a selective, orally active and irreversible EGFR tyrosine kinase inhibitor (EGFR TKI) with IC50 values ​​of 5, 4, 12 and 3 nM against Del, L858R and the double mutants T790M/L858R and
PubChem ID249820451
MDL NumberMFCD29079007
SMILESC=CC(=O)NC1CN(c2nc(Nc3cn(C)nc3OC)c3ncn(C)c3n2)CC1F
InChIInChI=1S/C18H22FN9O2/c1-5-13(29)21-11-8-28(6-10(11)19)18-23-15(14-16(24-18)26(2)9-20-14)22-12-7-27(3)25-17(12)30-4/h5,7,9-11H,1,6,8H2,2-4H3,(H,21,29)(H,22,23,24)/t10-,11-/m1/s1
InChI KeyJYIUNVOCEFIUIU-GHMZBOCLSA-N
MSDSmsds/93743_1_1776112_90_3.pdf
Transport InfoProduct name: mavelertinib
Related Products in Pharmaceutical Intermediates
allyl2-((3S,4R)-3-((R)-1-((tert-butyldimethylsilyl)oxy)ethyl)-2-oxo-4-(((propylthio)carbonothioyl)thio)azetidin-1-yl)-2-oxoacetate1392406-54-02A-9093690
(3R,6R)-3,6-OCTANEDIOL129619-37-02A-9093704
1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one1792180-81-42A-9093718
Cis-(3-Aza-Bicyclo[3.1.0]Hex-1-Yl)-Carbamic Acid Tert-Butyl Ester1250883-73-82A-9093741
(R)-5-BOC-5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID1454843-78-72A-9093742
Perfluoroheptanesulfonyl fluoride335-71-72A-9093766
5-ethyl-6-octyl-[1,2,3]triazolo[1,5-a]pyriMidin-7-aMine865318-97-42A-9093780
(1α,4α)-Bicyclo[2.2.2]octane-2,5-dione177931-43-02A-9093827
(R)-(-)-3,3'-BIS(TRIPHENYLSILYL)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE, 95%791616-55-22A-9093831
(R)-(+)-7,7'-BIS(DIPHENYLPHOSPHINO)-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE, MIN. 97% (R)-SDP917377-74-32A-9093832
Browse all Pharmaceutical Intermediates products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA