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GLYX 13

Name: GLYX 13
Brand: 2A Biotech
SKU: 2A-9093669

CAS Number117928-94-6

SynonymsL-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate; Thr-Pro-Pro-Thr-NH2 trifluoroacetate TPPT-amide trifluoroacetate; Rapastinel; GLYX 13

Molecular FormulaC18H31O6N5

Molecular Weight413.47

Purity98.00%%

MSDSChinese English

Cat. No.: 2A-9093669 Purity: 98.00%%

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Quality Control of [ 117928-94-6 ] Purity: 98.00%% SDS Specification MoL

Chemical & Physical Properties
CAS Number	117928-94-6
Catalog No.	2A-9093669
Chinese Name	雷帕替奈
Synonyms	L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate; Thr-Pro-Pro-Thr-NH2 trifluoroacetate TPPT-amide trifluoroacetate; Rapastinel; GLYX 13
Molecular Formula	C18H31O6N5
Molecular Weight	413.47
Purity	98.00%
Storage Condition	-20°C
Application	Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator with partial agonist properties.
PubChem ID	104164411
MDL Number	MFCD12912477
InChI	InChI=1S/C18H31N5O6/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27)/t9-,10-,11+,12+,13+,14+/m1/s1
InChI Key	GIBQQARAXHVEGD-BSOLPCOYSA-N
MSDS	msds/93669_1_117928_94_6.pdf
Bioactivity	Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Target: NMDARapastinel is a robust cognitive enhancer and facilitates hippocampal long-term potentiation (LTP) of synaptic transmission in slices. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Peptides References [1]. Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11. Chemical & Physical Properties Molecular Formula C18H31N5O6 Molecular Weight 413.46900 Exact Mass 413.22700 PSA 179.29000 Storage condition -20°C
Use of	Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Target: NMDARapastinel is a robust cognitive enhancer and facilitates hippocampal long-term potentiation (LTP) of synaptic transmission in slices. Properties Name GLYX-13 trifluoroacetate Synonym More Synonyms GLYX 13 TFA Biological Activity Description Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Target: NMDARapastinel is a robust cognitive enhancer and facilitates hippocampal long-term potentiation (LTP) of synaptic transmission in slices. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease References [1]. Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11. Chemical & Physical Properties Molecular Formula C18H31N5O6 Exact Mass 413.22700 PSA 179.29000
Transport Info	Product name: GLYX 13 TFA

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