CAS Number64706-54-3
SynonymsOrg 5730; Bepridil (INN); Bepadin; N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline; Vascor; Bepadin (TN); Cordium; CERM 1978
Molecular FormulaC24H34N2O
Molecular Weight366.54000
Purity95%
Density1.054 g/cm3
Boiling Point492.3ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 64706-54-3 |
| Catalog No. | 2A-9009364 |
| Chinese Name | 苄普地尔 |
| Synonyms | Org 5730; Bepridil (INN); Bepadin; N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline; Vascor; Bepadin (TN); Cordium; CERM 1978 |
| Molecular Formula | C24H34N2O |
| Molecular Weight | 366.54000 |
| Purity | 95 |
| Density | 1.054 g/cm3 |
| Boiling Point | 492.3ºC at 760 mmHg |
| Application | Beprodil (± - bepridil) is a calcium channel blocker used as an antiarrhythmic agent. Bephidil inhibits calcium and sodium currents and has research potential in some ischemia-induced ventricular arrh |
| HTC | 2933990090 |
| SMILES | CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1 |
| InChI | InChI=1S/C24H34N2O.ClH.H2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22;;/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3;1H;1H2 |
| InChI Key | UIEATEWHFDRYRU-UHFFFAOYSA-N |
| Use of | Properties Name bepridil Synonym More Synonyms BEPRIDIL HYDROCHLORIDE MONOHYDRATE Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV Calcium channel, Sodium channel, SARS-CoV-2[1][2] References [1]. Yatani A, et al. Bepridil block of cardiac calcium and sodium channels. J Pharmacol Exp Ther. 1986 Apr;237(1):9-17. [2]. Vatansever EC, et al. Bepridil is potent against SARS-CoV-2 in vitro. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2012201118. Chemical & Physical Properties Molecular Formula C24H34N2O Exact Mass 366.26700 PSA 15.71000 LogP 4.76810 Index of Refraction 1.572 InChIKey UIEATEWHFDRYRU-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : 1-Pyrrolidineethanamine, beta-((2-methylpropoxy)methyl)-N-phenyl-N-(phenylmeth yl)- CAS REGISTRY NUMBER : 64706-54-3 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C24-H34-N2-O MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Human - woman DOSE/DURATION : TOXIC EFFECTS : Cardiac - arrhythmias (including changes in conduction) REFERENCE : AHJOA2 American Heart Journal. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1925- Volume(issue)/page/year: 111,1005,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Human - man DOSE/DURATION : TOXIC EFFECTS : Cardiac - arrhythmias (including changes in conduction) REFERENCE : AHJOA2 American Heart Journal. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1925- Volume(issue)/page/year: 111,1005,1986 Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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