| Chemical & Physical Properties | |
|---|---|
| CAS Number | 918149-29-8 |
| Catalog No. | 2A-9093593 |
| Chinese Name | 精氨基琥珀酸 二钠盐 水合物 |
| Synonyms | Argininosuccinic acid hydrate disodium salt |
| Molecular Formula | C10H20N4Na2O7 |
| Molecular Weight | 334.24 (anhydrous basis) |
| Purity | ≥80 |
| Appearance | powder |
| Storage Condition | 20°C |
| Application | Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces redu |
| PubChem ID | 57653861 |
| MDL Number | MFCD11656132 |
| SMILES | O.[Na+].[Na+].N[C@@H](CCCNC(=N)N[C@@H](CC([O-])=O)C(O)=O)C([O-])=O |
| InChI | 1S/C10H18N4O6.2Na.H2O/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16;;;/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14);;;1H2/q;2*+1;/p-2/t5-,6-;;;/m0.../s1 |
| InChI Key | UCTAVRCIKYVVFI-VDBFCSKJSA-L |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/93593_1_918149_29_8.pdf |
| Bioactivity | Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244. [2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2023. Chemical & Physical Properties Molecular Formula C10H20N4Na2O7 Molecular Weight 354.26800 Exact Mass 354.11300 PSA 214.71000 InChIKey NIOYXHIHRCWMMB-USPAICOZSA-L SMILES NC(=NCCCC(N)C(=O)[O-])NC(CC(=O)[O-])C(=O)O.[Na+].[Na+] Storage condition 20°C |
| Use of | Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2]. Properties Name Argininosuccinic acid disodium salt hydrate Synonym More Synonyms Argininosuccinic acid disodium Biological Activity Description Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain[1][2]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Seminotti B, et al. Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency? Mol Neurobiol. 2020 Feb;57(2):1233-1244. [2]. Nagamani SCS, et al. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2023. Chemical & Physical Properties Molecular Formula C10H20N4Na2O7 Exact Mass 354.11300 PSA 214.71000 InChIKey NIOYXHIHRCWMMB-USPAICOZSA-L SMILES NC(=NCCCC(N)C(=O)[O-])NC(CC(=O)[O-])C(=O)O.[Na+].[Na+] |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 2-ACETYLCYCLOHEXANONE | 874-23-7 | 2A-9093585 |
| 2-Propenoic acid, 1-ethylcyclohexyl ester | 251909-25-8 | 2A-9093586 |
| SODIUM TETRADECYL SULFATE | 1191-50-0 | 2A-9093587 |
| 2-ethyl-3-hydroxyhexanal | 496-03-7 | 2A-9093588 |
| 3,7,11,15-TETRAMETHYL-1,6,10,14-HEXADECATETRAEN-3-OL | 68931-30-6 | 2A-9093592 |
| borogluconate | 87-46-7 | 2A-9093596 |
| 1-AMINOMETHYLPYRENE, HYDROCHLORIDE | 93324-65-3 | 2A-9093600 |
| 1-O-Acetyl- 2,3,4,6-tetra-O-benzyl-b-D-galactopyranose | 3866-62-4 | 2A-9093601 |
| POLY(L-LACTIDE) | 26161-42-2 | 2A-9093603 |
| DIISOBUTYLENE | 25167-70-8 | 2A-9093604 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS