| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1403254-99-8 |
| Catalog No. | 2A-9093450 |
| Chinese Name | Tazemetostat (EPZ-6438) |
| Synonyms | E7438; Tazemetostat; UNII-Q40W93WPE1; S7128,E7438; EPZ6438; EPZ-6438 |
| Molecular Formula | C34H44N4O4 |
| Molecular Weight | 572.74 |
| Purity | ≥98 (HPLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 750.8±60.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Tazemetostat (EPZ-6438) is a potent, selective, orally administered EZH2 inhibitor with Ki and IC50 of 2.5 and 11 nM, respectively. |
| PubChem ID | 85739282 |
| SMILES | CCN(C1CCOCC1)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C4=CC=C(C=C4)CN5CCOCC5 |
| InChI | InChI=1S/C34H44N4O4/c1-5-38(29-10-14-41-15-11-29)32-20-28(27-8-6-26(7-9-27)22-37-12-16-42-17-13-37)19-30(25(32)4)33(39)35-21-31-23(2)18-24(3)36-34(31)40/h6-9,18-20,29H,5,10-17,21-22H2,1-4H3,(H,35,39)(H,36,40) |
| InChI Key | NSQSAUGJQHDYNO-UHFFFAOYSA-N |
| NACRES Code | NA.41 |
| UNSPSC | 51101500 |
| MSDS | msds/93450_1_1403254_99_8.pdf |
| Transport Info | Product name: Tazemetostat (EPZ-6438) |
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