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Home > Products > Pharmaceutical R&D Materials > Heterocyclic Building Blocks > ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate
ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate structure, CAS 157115-85-0

ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate

CAS Number157115-85-0

SynonymsEthyl 1-(phenylacetyl)-L-prolylglycinate; Glycine, 1-(2-phenylacetyl)-L-prolyl-, ethyl ester; ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate; Noopept; N-phenylacetyl-L-prolylglycine ethyl ester; GVS-111; Nopept

Molecular FormulaC17H22N2O4

Molecular Weight318.37

Purity≥98 (HPLC)%

Density1.2±0.1 g/cm3

Boiling Point547.3±50.0 °C at 760 mmHg

Melting Point94.0 to 98.0 °C

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9093413 Purity: ≥98 (HPLC)%
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Quality Control of [ 157115-85-0 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number157115-85-0
Catalog No.2A-9093413
Chinese NameN-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯
SynonymsEthyl 1-(phenylacetyl)-L-prolylglycinate; Glycine, 1-(2-phenylacetyl)-L-prolyl-, ethyl ester; ethyl 2-[[(2S)-1-(2-phenylacetyl)pyrrolidine-2-carbonyl]amino]acetate; Noopept; N-phenylacetyl-L-prolylglycine ethyl ester; GVS-111; Nopept
Molecular FormulaC17H22N2O4
Molecular Weight318.37
Purity≥98 (HPLC)
Density1.2±0.1 g/cm3
Boiling Point547.3±50.0 °C at 760 mmHg
Melting Point94.0 to 98.0 °C
Appearancepowder
Storage Condition-20°C
ApplicationNoopept (GVS-111) is a peptide available as a dietary supplement.
HTC2942000000
PubChem ID329825678
MDL NumberMFCD00941121
SMILESO=C(CC1=CC=CC=C1)N2CCC[C@H]2C(NCC(OCC)=O)=O
InChI1S/C17H22N2O4/c1-2-23-16(21)12-18-17(22)14-9-6-10-19(14)15(20)11-13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3,(H,18,22)/t14-/m0/s1
InChI KeyPJNSMUBMSNAEEN-AWEZNQCLSA-N
NACRES CodeNA.77
UNSPSC12352200
MSDSmsds/93413_1_157115_85_0.pdf
Use ofProperties Name (S)-Ethyl 2-(1-(2-phenylacetyl)pyrrolidine-2-carboxamido)acetate Synonym More Synonyms Noopept Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease References [1]. Firstova IuIu, et al. Studying specific effects of nootropic drugs on glutamate receptors in the rat brain. Eksp Klin Farmakol. 2011;74(1):6-10. [2]. Pelsman A, et al. GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons. Int J Dev Neurosci. 2003 May;21(3):117-24. [3]. Ostrovskaya RU, et al. Memory restoring and neuroprotective effects of the proline-containing dipeptide, GVS-111, in a photochemical stroke model. Behav Pharmacol. 1999 Sep;10(5):549-53. [4]. Gudasheva TA, et al. The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine. Eur J Drug Metab Pharmacokinet. 1997 Jul-Sep;22(3):245-52. [5]. Kovalenko LP, et al. Anti-inflammatory properties of noopept (dipeptide nootropic agent GVS-111). Eksp Klin Farmakol. 2002 Mar-Apr;65(2):53-5. [6]. Kovalenko LP, et al. Preclinical study of noopept toxicity. Eksp Klin Farmakol. 2002 Jan-Feb;65(1):62-4. Chemical & Physical Properties Molecular Formula C17H22N2O4 Exact Mass 318.157959 PSA 75.71000 Index of Refraction 1.549 InChIKey PJNSMUBMSNAEEN-AWEZNQCLSA-N Safety Information RIDADR NONH for all modes of transport RTECS MC0814400 HS Code 2942000000 Synthetic Route Total: 1 Page (S)-1-(2-phenyl... CAS#:2752-38-7 CAS#:157115-85-0 Literature: European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157 Phenylacetyl ch... CAS#:103-80-0 CAS#:157115-85-0 Literature: European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157 CAS#:147-85-3 CAS#:157115-85-0 Literature: European Journal of Medicinal Chemistry, , vol. 31, # 2 p. 151 - 157 Precursor & DownStream Precursor 3 CAS#:2752-38-7 (S)-1-(2-phenyl... CAS#:103-80-0 Phenylacetyl ch... CAS#:147-85-3 DownStream 1 CAS#:157115-95-2 2-[[(2S)-1-(2-p...
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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