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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3650-73-5 |
| Catalog No. | 2A-9093044 |
| Chinese Name | 高肌肽 |
| Synonyms | L-homocarnosine; <4-Amino-butyryl>-L-histidin,Homocarnosin; L-HOMOCARNOSINE FREE BASE |
| Molecular Formula | C10H16N4O3 |
| Molecular Weight | 121.16 |
| Purity | ≥98 (perchloric acid titration) |
| Boiling Point | 646.9ºC at 760mmHg |
| Appearance | solid |
| Storage Condition | 2-8°C, sealed, dry |
| Application | Homocarnosine is a brain-specific dipeptide of gamma-aminobutyric acid (GABA) and histidine. Homocarnosine is an inhibitory neuromodulator synthesized from GABA in neurons and has anticonvulsant effec |
| HTC | 2933290090 |
| PubChem ID | 4140 |
| MDL Number | MFCD00064306 |
| SMILES | SCC([N+H3])C(=O)[O-] |
| InChI | 1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6) |
| InChI Key | XUJNEKJLAYXESH-UHFFFAOYSA-N |
| NACRES Code | NA.54 |
| eCl@ss | 32160406 |
| UNSPSC | 12352209 |
| MSDS | msds/93044_1_3650_73_5.pdf |
| Use of | Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects[1].Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation[2]. Properties Name .γ.-Aminobutyryl-L-histidine Synonym More Synonyms Homocarnosine Biological Activity Description Homocarnosine is a dipeptide of γ-aminobutyric acid (GABA) and histidine unique to brain. Homocarnosine is an inhibitory neuromodulator synthesized in the neuron from GABA and exhibiting anticonvulsant effects[1].Homocarnosine has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation[2]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor Human Endogenous Metabolite References [1]. O A Petroff, et al. Vigabatrin increases human brain homocarnosine and improves seizure control. Ann Neurol. 1998 Dec;44(6):948-52. [2]. Thanutchaporn Kumrungsee, et al. Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles. Amino Acids. 2020 May;52(5):743-753. Chemical & Physical Properties Molecular Formula C10H16N4O3 Exact Mass 240.12200 PSA 121.10000 LogP 0.35170 Index of Refraction 1.579 InChIKey CCLQKVKJOGVQLU-QMMMGPOBSA-N Safety Information WGK Germany 3 HS Code 2933290090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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