CAS Number75444-65-4
Synonyms4H-Pyrido(1,2-a)pyrimidin-4-one,3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl; 3-<2-(4-(4-fluorobenzoyl)piperidino)-ethyl>-2-methyl-4H-pyrido<1,2-a>-pyrimidin-4-one; 1-[2-(2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)ethyl]-4-(4-fluorobenzoyl)piperidine; Pirenperone; EINECS 278-213-5; Pirenperona [INN-Spanish]; Pirenperonum [INN-Latin]; R-47,465; 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]-ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
Molecular FormulaC23H24FN3O2
Molecular Weight393.45
Purity96.00%%
Density1.26g/cm3
Boiling Point556.3ºC at 760 mmHg
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 75444-65-4 |
| Catalog No. | 2A-9092930 |
| Chinese Name | 3-(2-(4-(4-氟苯甲酰基)哌啶-1-基)乙基)-2-甲基-4H-吡啶并[1,2-a]嘧啶-4-酮 |
| Synonyms | 4H-Pyrido(1,2-a)pyrimidin-4-one,3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-2-methyl; 3-<2-(4-(4-fluorobenzoyl)piperidino)-ethyl>-2-methyl-4H-pyrido<1,2-a>-pyrimidin-4-one; 1-[2-(2-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)ethyl]-4-(4-fluorobenzoyl)piperidine; Pirenperone; EINECS 278-213-5; Pirenperona [INN-Spanish]; Pirenperonum [INN-Latin]; R-47,465; 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]-ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
| Molecular Formula | C23H24FN3O2 |
| Molecular Weight | 393.45 |
| Purity | 96.00% |
| Density | 1.26g/cm3 |
| Boiling Point | 556.3ºC at 760 mmHg |
| Storage Condition | Room temperature, dry, sealed |
| Application | Peramperidone (R 47465) is a 5-HT2 serotonin receptor antagonist. Perenberon has moderate anxiolytic activity [1][2]. |
| PubChem ID | 855539 |
| SMILES | Cc1nc2ccccn2c(=O)c1CCN1CCC(C(=O)c2ccc(F)cc2)CC1 |
| InChI | InChI=1S/C23H24FN3O2/c1-16-20(23(29)27-12-3-2-4-21(27)25-16)11-15-26-13-9-18(10-14-26)22(28)17-5-7-19(24)8-6-17/h2-8,12,18H,9-11,13-15H2,1H3 |
| InChI Key | HXCNRYXBZNHDNE-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor References [1]. Krstić MK, et, al. Divergent effects of pirenperone, a 5-HT2 antagonist, on the pressor and tachycardic responses to 5-HT in guinea-pigs. Arch Int Physiol Biochim. 1983 Nov;91(4):345-9. [2]. Ansseau M, et, al. Pilot study of a specific serotonergic antagonist, pirenperone, in the treatment of anxiety disorders. Acta Psychiatr Belg. Sep-Oct 1983;83(5):517-24. Chemical & Physical Properties Density 1.26g/cm3 Boiling Point 556.3ºC at 760 mmHg Molecular Formula C23H24FN3O2 Molecular Weight 393.45 Flash Point 290.2ºC Exact Mass 393.18500 PSA 54.68000 LogP 3.21730 Index of Refraction 1.629 InChIKey HXCNRYXBZNHDNE-UHFFFAOYSA-N SMILES Cc1nc2ccccn2c(=O)c1CCN1CCC(C(=O)c2ccc(F)cc2)CC1 |
| Use of | Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2]. Properties Articles27 Name 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one Synonym More Synonyms Pirenperone Biological Activity Description Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor References [1]. Krstić MK, et, al. Divergent effects of pirenperone, a 5-HT2 antagonist, on the pressor and tachycardic responses to 5-HT in guinea-pigs. Arch Int Physiol Biochim. 1983 Nov;91(4):345-9. [2]. Ansseau M, et, al. Pilot study of a specific serotonergic antagonist, pirenperone, in the treatment of anxiety disorders. Acta Psychiatr Belg. Sep-Oct 1983;83(5):517-24. Chemical & Physical Properties Molecular Formula C23H24FN3O2 Exact Mass 393.18500 PSA 54.68000 LogP 3.21730 Index of Refraction 1.629 InChIKey HXCNRYXBZNHDNE-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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