CAS Number5950-12-9
SynonymsPiperlonguminine; (2E,4E)-5-(3,4-methylenedioxyphenyl)-2,4-pentadienoic acid N-isobutylamide; (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-isobutylpenta-2,4-dienamide; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide; (E,E)-Piperlonguminine; piperlongumine; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2,4-pentadienamide; 5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide; (2E,4E)-5-(1,3-Benzodioxol-5-yl)-N-isobutyl-2,4-pentadienamide; 5-(3',4'-methylenedioxy-phenyl)-2E,4E-pentadienoic acid isobutyl amide; mexedrone
Molecular FormulaC16H19NO3
Molecular Weight273.33
Purity≥90.0 (HPLC)%
Density1.1±0.1 g/cm3
Boiling Point476.9±45.0 °C at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 5950-12-9 |
| Catalog No. | 2A-9092867 |
| Chinese Name | Piperlonguminine |
| Synonyms | Piperlonguminine; (2E,4E)-5-(3,4-methylenedioxyphenyl)-2,4-pentadienoic acid N-isobutylamide; (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-isobutylpenta-2,4-dienamide; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide; (E,E)-Piperlonguminine; piperlongumine; (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2,4-pentadienamide; 5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide; (2E,4E)-5-(1,3-Benzodioxol-5-yl)-N-isobutyl-2,4-pentadienamide; 5-(3',4'-methylenedioxy-phenyl)-2E,4E-pentadienoic acid isobutyl amide; mexedrone |
| Molecular Formula | C16H19NO3 |
| Molecular Weight | 273.33 |
| Purity | ≥90.0 (HPLC) |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 476.9±45.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8℃ |
| Application | Piperlonguminine is an alkaloid amide isolated from Piper. Piperlonguminine has a variety of biological properties, including anti-inflammatory, anti-tumor, neuroprotective, anti-platelet, anti-melano |
| HTC | 2932999099 |
| PubChem ID | 417582 |
| MDL Number | MFCD15146947 |
| SMILES | N(CC(C)C)C(=O)\C=C\C=C\c1cc2c(cc1)OCO2 |
| InChI | InChI=1S/C16H19NO3/c1-12(2)10-17-16(18)6-4-3-5-13-7-8-14-15(9-13)20-11-19-14/h3-9,12H,10-11H2,1-2H3,(H,17,18)/b5-3+,6-4+ |
| InChI Key | WHAAPCGHVWVUEX-GGWOSOGESA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/92867_1_5950_12_9.pdf |
| Use of | Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4]. Properties Name Piperlonguminine Synonym More Synonyms Piperlonguminine Biological Activity Description Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4]. Related Catalog Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial References [1]. Bezerra DP, et, al. In vivo growth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from the Piper species. J Appl Toxicol. 2008 Jul; 28(5): 599-607. [2]. Yang T, et, al. Piperlonguminine is neuroprotective in experimental rat stroke. Int Immunopharmacol. 2014 Dec; 23(2): 447-51. [3]. Marques JV, et, al. Antifungal amides from Piper scutifolium and Piper hoffmanseggianum. J Nat Prod. 2007 Dec; 70(12):2036-9. [4]. Chy MNU, et, al. Antibacterial, anthelmintic, and analgesic activities of Piper sylvaticum (Roxb.) leaves and in silico molecular docking and PASS prediction studies of its isolated compounds. J Complement Integr Med. 2019 Aug 22;16(4). Chemical & Physical Properties Molecular Formula C16H19NO3 Exact Mass 273.136505 PSA 47.56000 Index of Refraction 1.577 InChIKey WHAAPCGHVWVUEX-GGWOSOGESA-N Storage condition 2-8℃ Safety Information HS Code 2932999099 Synthetic Route Isobutylamine (E,E)-Piperic A... Piperlonguminin... Literature: Sangwan, Payare L.; Koul, Jawahir L.; Koul, Surrinder; Reddy, Mallepally V.; Thota, Niranjan; Khan, Inshad A.; Kumar, Ashwani; Kalia, Nitin P.; Qazi, Ghulam N. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9847 - 9857 Isobutylamine piperic acid ch... Piperlonguminin... Literature: De Paula, Vanderlucia F.; De A Barbosa, Luiz C.; Demuner, Antonio J.; Pilo-Veloso, Dorila; Picanco, Marcelo C. Pest Management Science, 2000 , vol. 56, # 2 p. 168 - 174 2-[(E)-3,4-(met... 736947-73-2 Piperlonguminin... Literature: Li, Yang; Zhang, Yu; Huang, Zhi; Cao, Xiaoping; Gao, Kun Canadian Journal of Chemistry, 2004 , vol. 82, # 5 p. 622 - 630 Precursor & DownStream Precursor 9 CAS#:78-81-9 Isobutylamine CAS#:136-72-1 (E,E)-Piperic Acid CAS#:736947-73-2 2-[(E)-3,4-(met... CAS#:2373-80-0 (2E)-3-(1,3-Ben... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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