CAS Number37839-81-9
SynonymsAdenosine 3',5'-cyclic monophosphate sodium salt monohydrate; 3',5'-Cyclic AMP sodium salt; Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate; 3',5'-Cyclic AMP Sodium Salt Hydrate; Adenosine 3',5'-cyclic monophosphate sodium salt monohydrate; MFCD00069736; CAMP SODIUM SALT
Molecular FormulaC10H11N5NaO6P
Molecular Weight369.20
Purity≥98.0 (HPLC)%
Boiling Point701.5ºC at 760 mmHg
Melting Point219 - 220ºC
Appearancepowder
Symbol
Signal WordWarning
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 37839-81-9 |
| Catalog No. | 2A-9092836 |
| Chinese Name | 腺苷-3',5'-环磷酸酯钠 |
| Synonyms | Adenosine 3',5'-cyclic monophosphate sodium salt monohydrate; 3',5'-Cyclic AMP sodium salt; Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate; 3',5'-Cyclic AMP Sodium Salt Hydrate; Adenosine 3',5'-cyclic monophosphate sodium salt monohydrate; MFCD00069736; CAMP SODIUM SALT |
| Molecular Formula | C10H11N5NaO6P |
| Molecular Weight | 369.20 |
| Purity | ≥98.0 (HPLC) |
| Boiling Point | 701.5ºC at 760 mmHg |
| Melting Point | 219 - 220ºC |
| Appearance | powder |
| Water Solubility | H2O: 50 mg/mL | Soluble in water (50 mg/ml). |
| Storage Condition | Sealed, cool and dry storage |
| Application | Sodium cyclic adenosine monophosphate, a derivative of adenosine triphosphate, is an intracellular signaling molecule responsible for guiding the cell's response to extracellular signals. Sodium cycli |
| HTC | 29349990 |
| PubChem ID | 24891151 |
| MDL Number | MFCD00069736 |
| SMILES | [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O |
| InChI | 1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1 |
| InChI Key | BXJBFCKTIWRKMQ-MCDZGGTQSA-M |
| Beilstein/REAXYS | 54612 |
| NACRES Code | NA.77 |
| eCl@ss | 32160414 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| MSDS | msds/92836_1_37839_81_9.pdf |
| Bioactivity | Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3]. Related Catalog Research Areas >> Cancer Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Target Human Endogenous Metabolite Microbial Metabolite In Vitro Cyclic AMP (Cyclic adenosine monophosphate) sodium modulates mediator generation. Cyclic AMP sodium suppresses the expression of pro-inflammatory cytokines, including TNF-α and IL-12, and enhances the production of the anti-inflammatory cytokine IL-10. References [1]. G M Fimia, et al. Cyclic AMP signaling. J Cell Sci. 2001 Jun;114(Pt 11):1971-2. [2]. Paolo Sassone-Corsi, et al. The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148. [3]. Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon Cytokine Res. 2006 Nov;26(11):827-33. Chemical & Physical Properties Boiling Point 701.5ºC at 760 mmHg Melting Point 219 - 220ºC Molecular Formula C10H11N5NaO6P Molecular Weight 351.19 Flash Point 378ºC Exact Mass 351.034454 PSA 167.48000 LogP 0.20200 InChIKey QJOMQLIYJMMGDA-MCDZGGTQSA-N SMILES Nc1ncnc2c1ncn2C1OC2COP(=O)(O)OC2C1O.[Na] Storage condition −20°C Water Solubility H2O: 50 mg/mL | Soluble in water (50 mg/ml). |
| Use of | Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3]. Properties Articles154 Name 3',5'-cAMP Na Hydrate Synonym More Synonyms camp sodium salt Biological Activity Description Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3]. Related Catalog Research Areas >> Cancer Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Human Endogenous Metabolite Microbial Metabolite In Vitro Cyclic AMP (Cyclic adenosine monophosphate) sodium modulates mediator generation. Cyclic AMP sodium suppresses the expression of pro-inflammatory cytokines, including TNF-α and IL-12, and enhances the production of the anti-inflammatory cytokine IL-10. References [1]. G M Fimia, et al. Cyclic AMP signaling. J Cell Sci. 2001 Jun;114(Pt 11):1971-2. [2]. Paolo Sassone-Corsi, et al. The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148. [3]. Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon Cytokine Res. 2006 Nov;26(11):827-33. Chemical & Physical Properties Molecular Formula C10H11N5NaO6P Exact Mass 351.034454 PSA 167.48000 LogP 0.20200 InChIKey QJOMQLIYJMMGDA-MCDZGGTQSA-N |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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