CAS Number74863-84-6
SynonymsNovastan; Argatroban; MQPA; Argipidine; Slonnon; Argatroban monohydrate; MFCD00866789; Argatroban anhydrous; UNII:IY90U61Z3S; UNII:OCY3U280Y3
Molecular FormulaC23H36O5N6S1
Molecular Weight508.64
Purity98%
Density1.5±0.1 g/cm3
Boiling Point801.3±75.0 °C at 760 mmHg
Melting Point188-1890C
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 74863-84-6 |
| Catalog No. | 2A-9009233 |
| Chinese Name | 阿加曲班(MCI-9038) |
| Synonyms | Novastan; Argatroban; MQPA; Argipidine; Slonnon; Argatroban monohydrate; MFCD00866789; Argatroban anhydrous; UNII:IY90U61Z3S; UNII:OCY3U280Y3 |
| Molecular Formula | C23H36O5N6S1 |
| Molecular Weight | 508.64 |
| Purity | 98 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 801.3±75.0 °C at 760 mmHg |
| Melting Point | 188-1890C |
| Appearance | white powder |
| Storage Condition | Store at +4°C |
| Packaging | III |
| Application | Argatroban is a selective inhibitor of thrombin. |
| HTC | 2935009090 |
| MDL Number | MFCD00866789 |
| SMILES | CC1CNc2c(cccc2S(=O)(=O)NC(CCCN=C(N)N)C(=O)N2CCC(C)CC2C(=O)O)C1 |
| InChI | InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15?,17?,18-/m1/s1 |
| InChI Key | KXNPVXPOPUZYGB-IOVMHBDKSA-N |
| Hazard Symbols | 6.1 |
| MSDS | msds/9233_1_74863_84_6.pdf |
| Use of | Properties Name Argatroban anhydrous Synonym More Synonyms Argatroban Biological Activity Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Thrombin Natural Products >> Alkaloid Research Areas >> Cardiovascular Disease References [1]. Kawada, T., et al., Argatroban, an attractive anticoagulant, for left heart bypass with centrifugal pump for repair of traumatic aortic rupture. Jpn J Thorac Cardiovasc Surg, 1999. 47(3): p. 104-9. [2]. Jang, I.K., et al., A multicenter, randomized study of argatroban versus heparin as adjunct to tissue plasminogen activator (TPA) in acute myocardial infarction: myocardial infarction with novastan and TPA (MINT) study. J Am Coll Cardiol, 1999. 33(7): p. 1879-85. Chemical & Physical Properties Molecular Formula C23H36N6O5S Exact Mass 508.246796 PSA 186.09000 Index of Refraction 1.674 InChIKey KXNPVXPOPUZYGB-IOVMHBDKSA-N Safety Information Hazard Codes Xn,N Safety Phrases S28-S61-S28A WGK Germany 2 RTECS SK2450000 Packaging Group III Hazard Class 6.1 HS Code 2935009090 Synthetic Route (2R,4R)-1-[(2S)... CAS#:74874-10-5 Argatroban CAS#:74863-84-6 benzyl (2R,4R)-... CAS#:367952-84-9 Argatroban CAS#:74863-84-6 Literature: Cossy, Janine; Belotti, Damien Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 15 p. 1989 - 1992 4-Pipecoline CAS#:626-58-4 Argatroban CAS#:74863-84-6 Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 15 p. 1989 - 1992 Precursor & DownStream Precursor 6 CAS#:74874-10-5 (2R,4R)-1-[(2S)... CAS#:367952-84-9 benzyl (2R,4R)-... CAS#:626-58-4 4-Pipecoline CAS#:123387-50-8 1-BOC-4-METHYLP... DownStream 0 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Product name: Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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