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Andrograpanin structure, CAS 82209-74-3

Andrograpanin

CAS Number82209-74-3

Synonyms3,14-Dideoxyandrographolide; andrograpanin

Molecular FormulaC20H30O3

Molecular Weight318.45

Purity≥95.0 (HPLC)%

Density1.09

Boiling Point

Melting Point106-107ºC

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

SymbolTransport

Signal WordWarning

Cat. No.: 2A-9009196 Purity: ≥95.0 (HPLC)%
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Quality Control of [ 82209-74-3 ] Purity: ≥95.0 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number82209-74-3
Catalog No.2A-9009196
Chinese Name新穿心莲内酯苷元
Synonyms3,14-Dideoxyandrographolide; andrograpanin
Molecular FormulaC20H30O3
Molecular Weight318.45
Purity≥95.0 (HPLC)
Density1.09
Melting Point106-107ºC
Appearancesolid
Storage ConditionRoom temperature, dry, sealed
ApplicationAndrographol is a bioactive compound extracted from Andrographis paniculata and has anti-inflammatory and anti-infective properties [1][2].
MDL NumberMFCD07778568
SMILESC[C@@]1(CO)CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12
InChI1S/C20H30O3/c1-14-5-8-17-19(2,13-21)10-4-11-20(17,3)16(14)7-6-15-9-12-23-18(15)22/h9,16-17,21H,1,4-8,10-13H2,2-3H3/t16-,17-,19+,20+/m1/s1
InChI KeyWKKBRRFSRMDTJB-JYBIWHBTSA-N
NACRES CodeNA.24
UNSPSC41116107
Hazard SymbolsTransport
MSDSmsds/9196_1_82209_74_3.pdf
BioactivityAndrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology In Vitro Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways[1]. Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells[2]. References [1]. 1.Li-Li Ji, et al.Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1alpha-induced leukocytes chemotaxis. J Cell Biochem. 2005 Aug 1;95(5):970-8. [2]. 2.Jun Liu, et al. Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. Int Immunopharmacol. 2008 Jul;8(7):951-8. Chemical & Physical Properties Density 1.09 Melting Point 106-107ºC Molecular Formula C20H30O3 Molecular Weight 318.45000 Exact Mass 318.21900 PSA 46.53000 LogP 4.02100 InChIKey WKKBRRFSRMDTJB-JYBIWHBTSA-N SMILES C=C1CCC2C(C)(CO)CCCC2(C)C1CCC1=CCOC1=O
Use ofAndrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2]. Properties Name 4-[2-[(1R,4aS,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one Synonym More Synonyms Biological Activity Description Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2]. Related Catalog Research Areas >> Infection Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology In Vitro Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways[1]. Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells[2]. References [2]. 2.Jun Liu, et al. Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. Int Immunopharmacol. 2008 Jul;8(7):951-8. Chemical & Physical Properties Molecular Formula C20H30O3 Exact Mass 318.21900 PSA 46.53000 LogP 4.02100 InChIKey WKKBRRFSRMDTJB-JYBIWHBTSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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