CAS Number76896-80-5
Synonyms(3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane; 2E,4E,7E-undecatriene-1-triazine; Antibiotic WS-1228A; WS 1228A; Triacsincapprox.; triacsin c from streptomyces sp.; Triacsin C; 2,4,7-Undecatrienal; WS1228A; Galloflavin; 2E,4E,7E-UNDECATRIENE-1-TRIAZENE; 1-hydroxy-3-(E,E,E,-2',4',7'-undecatrienylidine)triazene
Molecular FormulaC11H17N3O
Molecular Weight207.27
Purity98%
Density0.9±0.1 g/cm3
Boiling Point320.7±45.0 °C at 760 mmHg
Melting Point100-102ºC
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 76896-80-5 |
| Catalog No. | 2A-9091601 |
| Chinese Name | 三氮菌素 C |
| Synonyms | (3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane; 2E,4E,7E-undecatriene-1-triazine; Antibiotic WS-1228A; WS 1228A; Triacsincapprox.; triacsin c from streptomyces sp.; Triacsin C; 2,4,7-Undecatrienal; WS1228A; Galloflavin; 2E,4E,7E-UNDECATRIENE-1-TRIAZENE; 1-hydroxy-3-(E,E,E,-2',4',7'-undecatrienylidine)triazene |
| Molecular Formula | C11H17N3O |
| Molecular Weight | 207.27 |
| Purity | 98 |
| Density | 0.9±0.1 g/cm3 |
| Boiling Point | 320.7±45.0 °C at 760 mmHg |
| Melting Point | 100-102ºC |
| Appearance | powder |
| Storage Condition | -20°C |
| Application | Triacsin C (WS 1228A), derived from Streptomyces aureofaciens, is a natural intracellular long-chain acyl-CoA synthetase (ACSL) inhibitor. Triacsin C inhibits the accumulation of TAG into lipid drople |
| PubChem ID | 24900214 |
| MDL Number | MFCD00798237 |
| SMILES | CCC\C=C\C\C=C\C=C\C=N\NN=O |
| InChI | 1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+ |
| InChI Key | NKTGCVUIESDXPU-YLEPRARLSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 51111800 |
| Hazard Symbols | transportation |
| MSDS | msds/91601_1_76896_80_5.pdf |
| Bioactivity | Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others Target ACSL[1] References [1]. Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411. [2]. Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8. Chemical & Physical Properties Density 0.9±0.1 g/cm3 Boiling Point 320.7±45.0 °C at 760 mmHg Melting Point 100-102ºC Molecular Formula C11H17N3O Molecular Weight 207.272 Flash Point 147.7±28.7 °C Exact Mass 207.137161 PSA 53.82000 LogP 4.02 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.485 InChIKey NKTGCVUIESDXPU-UHFFFAOYSA-N SMILES CCCC=CCC=CC=CC=NNN=O Storage condition -20°C |
| Use of | Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2]. Properties Articles32 Name triacsin c Synonym More Synonyms Triacsin C from Streptomyces sp. Biological Activity Description Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411. [2]. Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8. Chemical & Physical Properties Molecular Formula C11H17N3O Exact Mass 207.137161 PSA 53.82000 Index of Refraction 1.485 InChIKey NKTGCVUIESDXPU-UHFFFAOYSA-N SMILES CCCC=CCC=CC=CC=NNN=O |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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