CAS Number7412-78-4
SynonymsN-glycylglutamic acid; H2N-glycine-Acide glutamique-OH; EINECS 231-019-4; H-Gly-Glu-OH; Glycylglutamic acid; Gly-L-Glu-OH; L-Glutamic acid,N-glycyl; GLY-GLU; MFCD00008128; Glycyl-L-glutamic acid; N-glycyl-L-glutamic acid; Gly-Glu-OH
Molecular FormulaC7H12N2O5
Molecular Weight204.18
Purity≥98 (TLC)%
Density1.4±0.1 g/cm3
Boiling Point536.6±50.0 °C at 760 mmHg
Melting Point155-158 °C
Appearancepowder
EINECS231-019-4
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 7412-78-4 |
| Catalog No. | 2A-9091507 |
| Chinese Name | 甘氨酰谷氨酸 |
| Synonyms | N-glycylglutamic acid; H2N-glycine-Acide glutamique-OH; EINECS 231-019-4; H-Gly-Glu-OH; Glycylglutamic acid; Gly-L-Glu-OH; L-Glutamic acid,N-glycyl; GLY-GLU; MFCD00008128; Glycyl-L-glutamic acid; N-glycyl-L-glutamic acid; Gly-Glu-OH |
| Molecular Formula | C7H12N2O5 |
| Molecular Weight | 204.18 |
| Purity | ≥98 (TLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 536.6±50.0 °C at 760 mmHg |
| Melting Point | 155-158 °C |
| Appearance | powder |
| Storage Condition | Sealed in a cool, dry environment at -20ºC. |
| Application | Glycyl-L-glutamate is a neurotrophic factor (NF) in the body that maintains the content and activity of acetylcholinesterase. Glycyl-L-glutamic acid does not directly act on the synthesis of acetylcho |
| EINECS | 231-019-4 |
| HTC | 2924199090 |
| PubChem ID | 24895026 |
| MDL Number | MFCD00008128 |
| SMILES | NCC(=O)N[C@@H](CCC(O)=O)C(O)=O |
| InChI | 1S/C7H12N2O5/c8-3-5(10)9-4(7(13)14)1-2-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m0/s1 |
| InChI Key | IEFJWDNGDZAYNZ-BYPYZUCNSA-N |
| NACRES Code | NA.26 |
| UNSPSC | 12352209 |
| Hazard Symbols | transportation |
| MSDS | msds/91507_1_7412_78_4.pdf |
| Bioactivity | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn't act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE Target Acetylcholinesterase References [1]. Koelle GB, et al. Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo. Proc Natl Acad Sci U S A. 1985 Aug;82(15):5213-7. [2]. Yourick JJ, et al. Regeneration of acetylcholinesterase in clonal neuroblastoma-glioma hybrid NG108-15 cells after soman inhibition: effect of glycyl-L-glutamine. Cell Biol Toxicol. 1991 Jul;7(3):229-37. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 536.6±50.0 °C at 760 mmHg Melting Point 155-158ºC (dec.)(lit.) Molecular Formula C7H12N2O5 Molecular Weight 204.181 Flash Point 278.3±30.1 °C Exact Mass 204.074615 PSA 129.72000 LogP -2.68 Vapour Pressure 0.0±3.1 mmHg at 25°C Index of Refraction 1.537 InChIKey IEFJWDNGDZAYNZ-BYPYZUCNSA-N SMILES NCC(=O)NC(CCC(=O)O)C(=O)O Storage condition −20°C |
| Use of | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn't act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2]. Properties Articles24 Name (2S)-2-[(2-aminoacetyl)amino]pentanedioic acid Synonym More Synonyms β-Endorphin (30-31) (human) Biological Activity Description Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn't act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration[1][2]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE Acetylcholinesterase References [1]. Koelle GB, et al. Glycyl-L-glutamine, a precursor, and glycyl-L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat in vivo. Proc Natl Acad Sci U S A. 1985 Aug;82(15):5213-7. Chemical & Physical Properties Molecular Formula C7H12N2O5 Exact Mass 204.074615 PSA 129.72000 LogP -2.68 Index of Refraction 1.537 InChIKey IEFJWDNGDZAYNZ-BYPYZUCNSA-N SMILES NCC(=O)NC(CCC(=O)O)C(=O)O |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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