CAS Number71751-41-2
SynonymsMFCD01769550; EINECS 200-096-6; avomec; mk936; zephyr; affirm; SADDLE; Zephy; AVM; avidec; Avermectin B1; ACIMIC; avid
Molecular FormulaC95H142O28
Molecular Weight1732.13
Purity98%
Density1.2±0.1 g/cm3
Boiling Point940.9±65.0 °C at 760 mmHg
Melting Point150-155°C
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 71751-41-2 |
| Catalog No. | 2A-9009022 |
| Chinese Name | 阿维菌素 |
| Synonyms | MFCD01769550; EINECS 200-096-6; avomec; mk936; zephyr; affirm; SADDLE; Zephy; AVM; avidec; Avermectin B1; ACIMIC; avid |
| Molecular Formula | C95H142O28 |
| Molecular Weight | 1732.13 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 940.9±65.0 °C at 760 mmHg |
| Melting Point | 150-155°C |
| Appearance | white powder |
| Storage Condition | 1.0% EC is packed in 100ml plastic bottles or 200L |
| Packaging | II |
| Application | Avermectin B1 (Abamectin) is an anthelmintic insecticide. |
| HTC | 2932999099 |
| PubChem ID | 329753906 |
| MDL Number | MFCD01769550 |
| SMILES | CCC(C)C1O[C@@]2(C[C@@H]3CC(C\C=C(C)\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\C=C\C=C6/COC7[C@H](O)C(C)=CC(C(=O)O3)[C@]67O)O2)C=C[C@@H]1C |
| InChI | 1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35?,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 |
| InChI Key | RRZXIRBKKLTSOM-RDKIRRGNSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 6.1(a) |
| MSDS | msds/9022_1_71751_41_2.pdf |
| Use of | Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. IC50 Value: N/ATarget: AntiparasiticAvermectin B1 is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Avermectin B1 is a natural fermentation product of this bacterium. Properties Articles29 Name Abamectin Synonym More Synonyms Avermectin Biological Activity Description Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. IC50 Value: N/ATarget: AntiparasiticAvermectin B1 is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Avermectin B1 is a natural fermentation product of this bacterium. Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [2]. De Chaneet GC, Casey R, Dixon FF, Besier RB, Mitchell RK.Effect of avermectin B1 and benzimidazole anthelmintics on worm egg output of treated cattle.Aust Vet J. 1988 Mar;65(3):85-6. [3]. Seaman JT, Eagleson JS, Carrigan MJ, Webb RF.Avermectin B1 toxicity in a herd of Murray Grey cattle.Aust Vet J. 1987 Sep;64(9):284-5. [4]. Murty US, Jyothi KN, Jamil K.Effect of avermectin B1 (L-676) a metabolite from Streptomyces avermilitis on immatures of Culex quinquefasciatus.Indian J Med Res. 1987 May;85:539-41. [5]. Parrish MD, Roberts RB.Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae).J Econ Entomol. 1984 Jun;77(3):769-72. Chemical & Physical Properties Molecular Formula C95H142O28 PSA 170.06000 Index of Refraction 1.571 Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Avermectin B(sub 1) CAS REGISTRY NUMBER : 71751-41-2 LAST UPDATED : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,3,1989 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(249-250),41,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 13600 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(249-250),41,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1740 ug/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 60,289,1992 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Primate - monkey DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(249-250),41,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(249-250),41,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Bird - duck DOSE/DURATION : 84600 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(249-250),41,1988 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Bird - domestic DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(249-250),41,1988 Safety Information GHS06, GHS08, GHS09 Signal Word Danger Hazard Statements H300 + H330-H361d-H372-H410 Precautionary Statements P201-P260-P273-P301 + P310 + P330-P304 + P340 + P310-P403 + P233 Target Organs Nervous system Personal Protective Equipment Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter Hazard Codes T+,N Risk Phrases R20 RIDADR 2588 RTECS CL1203000 Packaging Group II Hazard Class 6.1(a) HS Code 2932999099 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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