CAS Number120-08-1
SynonymsMFCD00006871; 6,7-Dimethoxy-chromen-2-one; Scoparone; EINECS 204-369-0; Dimethylesculetin; 6,7-dimethoxychromen-2-one; 6,7-Dimethoxy-2H-chromen-2-one
Molecular FormulaC11H10O4
Molecular Weight206.195
Purity98%
Density1.2±0.1 g/cm3
Boiling Point369.2±42.0 °C at 760 mmHg
Melting Point145°C
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 120-08-1 |
| Catalog No. | 2A-9009002 |
| Chinese Name | 滨蒿內酯 |
| Synonyms | MFCD00006871; 6,7-Dimethoxy-chromen-2-one; Scoparone; EINECS 204-369-0; Dimethylesculetin; 6,7-dimethoxychromen-2-one; 6,7-Dimethoxy-2H-chromen-2-one |
| Molecular Formula | C11H10O4 |
| Molecular Weight | 206.195 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 369.2±42.0 °C at 760 mmHg |
| Melting Point | 145°C |
| Appearance | white powder |
| Storage Condition | Store at room temperature in a cool and ventilated |
| Packaging | III |
| Application | Scoparone is isolated from Artemisia vulgaris and has anticoagulant, antivasodilatory, and anti-inflammatory activities. |
| HTC | 2932209090 |
| SMILES | COc1cc2ccc(=O)oc2cc1OC |
| InChI | InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3 |
| InChI Key | GUAFOGOEJLSQBT-UHFFFAOYSA-N |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/9002_2_120_08_1.pdf |
| Bioactivity | Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others In Vitro Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM[1]. In Vivo Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats[1]. Animal Model: Chronic Pancreatitis (CP) Rat Models[1] Dosage: 30 mg/kg, 60 mg/kg Administration: Oral administration; 30 mg/kg, 60 mg/kg; 4 weeks Result: Protected against pancreatic damage References [1]. Xu M, et al. Scoparone Protects Against Pancreatic Fibrosis via TGF-β/Smad Signaling in Rats. Cell Physiol Biochem. 2016;40(1-2):277-286. Epub 2016 Nov 18. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 369.2±42.0 °C at 760 mmHg Melting Point 145°C Molecular Formula C11H10O4 Molecular Weight 206.195 Flash Point 166.8±27.9 °C Exact Mass 206.057907 PSA 48.67000 LogP 1.60 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.557 InChIKey GUAFOGOEJLSQBT-UHFFFAOYSA-N SMILES COc1cc2ccc(=O)oc2cc1OC |
| Use of | Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. Properties Articles30 Name 6,7-Dimethoxycoumarin Synonym More Synonyms Scoparone Biological Activity Description Scoparone is isolated from Artemisia capillaris, has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others In Vitro Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM[1]. References [1]. Xu M, et al. Scoparone Protects Against Pancreatic Fibrosis via TGF-β/Smad Signaling in Rats. Cell Physiol Biochem. 2016;40(1-2):277-286. Epub 2016 Nov 18. Chemical & Physical Properties Molecular Formula C11H10O4 Exact Mass 206.057907 PSA 48.67000 Index of Refraction 1.557 InChIKey GUAFOGOEJLSQBT-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (6,7-Dimethoxy-2-benzopyrone) IMDG Code: TOXIC SOLID, ORGANIC, N.O.S. (6,7-Dimethoxy-2-benzopyrone) International air transport hazard regulations: Toxic solid, organic, n.o.s. (6,7-Dimethoxy-2-benzopyrone) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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