CAS Number533-75-5
Synonyms2-hydroxycyclohepta-2,4,6-trien-1-one; 2-Hydroxy-2,4,6-cycloheptatrienone; 2-hydroxy-2,4,6-cycloheptatriene-1-one; Purpurocatechol; 2-hydroxytropone; 2-hydroxi-2,4,6-cycloheptatrien-1-one; EINECS 208-577-2; Tropolone; a-Tropolone; 2-hydroxycyclohepta-2,4,6-trienone; MFCD00004158; 2-Hydroxy-2,4,6-cycloheptatrien-1-one
Molecular FormulaC7H6O2
Molecular Weight122.12
Purity98%
Density1.3±0.1 g/cm3
Boiling Point80-84 °C/0.1 mmHg (lit.)
Melting Point50-52 °C (lit.)
AppearanceLight yellow-cream solid
EINECS208-577-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 533-75-5 |
| Catalog No. | 2A-9008890 |
| Chinese Name | 环庚三烯酚酮 |
| Synonyms | 2-hydroxycyclohepta-2,4,6-trien-1-one; 2-Hydroxy-2,4,6-cycloheptatrienone; 2-hydroxy-2,4,6-cycloheptatriene-1-one; Purpurocatechol; 2-hydroxytropone; 2-hydroxi-2,4,6-cycloheptatrien-1-one; EINECS 208-577-2; Tropolone; a-Tropolone; 2-hydroxycyclohepta-2,4,6-trienone; MFCD00004158; 2-Hydroxy-2,4,6-cycloheptatrien-1-one |
| Molecular Formula | C7H6O2 |
| Molecular Weight | 122.12 |
| Purity | 98 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 80-84 °C/0.1 mmHg (lit.) |
| Melting Point | 50-52 °C (lit.) |
| Appearance | Light yellow-cream solid |
| Water Solubility | Water solubility: soluble |
| Storage Condition | Store in a cool, dry, well-ventilated warehouse. K |
| Application | Tropolone is a tropone derivative with a hydroxyl group at the 2-position, and is the precursor of many Azulene derivatives, such as 2-methylazulene-1-carboxylate. Tropolone is a potent mushroom tyros |
| EINECS | 208-577-2 |
| HTC | 29144090 |
| PubChem ID | 24900578 |
| MDL Number | MFCD00004158 |
| SMILES | OC1=CC=CC=CC1=O |
| InChI | 1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9) |
| InChI Key | MDYOLVRUBBJPFM-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1904978 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | Transport |
| Safety Description | S24/25 |
| MSDS | msds/8890_1_533_75_5.pdf |
| Bioactivity | Tropolone, a tropone derivative with a hydroxyl group in the 2-position, is a precursor of manyazulene derivatives such as methyl 2-methylazulene-1-carboxylate[1]. Tropolone is a potent inhibitor of mushroom tyrosinase with a IC50 of 0.4 μM, and the inhibition can be reversed by dialysis or by excess CU2+[2]. Related Catalog Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase Target IC50: 0.4 μM (mushroom tyrosinase)[2] References [1]. Donald D Nolting,et al. Synthesis of bicyclo[5.3.0]azulene derivatives. Nat Protoc. 2009; 4(8): 1113-1117. [2]. VardaKahn, et al.Inhibition of mushroom tyrosinase by tropolone Phytochemistry. Volume 24, Issue 5, 1985, Pages 905-908 Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 290.1±33.0 °C at 760 mmHg Melting Point 50-52 °C(lit.) Molecular Formula C7H6O2 Molecular Weight 122.121 Flash Point 122.0±18.0 °C Exact Mass 122.036781 PSA 37.30000 LogP 0.42 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.603 InChIKey MDYOLVRUBBJPFM-UHFFFAOYSA-N SMILES O=c1cccccc1O Storage condition 2-8°C |
| Use of | Tropolone, a tropone derivative with a hydroxyl group in the 2-position, is a precursor of manyazulene derivatives such as methyl 2-methylazulene-1-carboxylate[1]. Tropolone is a potent inhibitor of mushroom tyrosinase with a IC50 of 0.4 μM, and the inhibition can be reversed by dialysis or by excess CU2+[2]. Properties Articles37 Name Tropolone Synonym More Synonyms Tropolone Biological Activity Description Tropolone, a tropone derivative with a hydroxyl group in the 2-position, is a precursor of manyazulene derivatives such as methyl 2-methylazulene-1-carboxylate[1]. Tropolone is a potent inhibitor of mushroom tyrosinase with a IC50 of 0.4 μM, and the inhibition can be reversed by dialysis or by excess CU2+[2]. Related Catalog Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase IC50: 0.4 μM (mushroom tyrosinase)[2] References [1]. Donald D Nolting,et al. Synthesis of bicyclo[5.3.0]azulene derivatives. Nat Protoc. 2009; 4(8): 1113-1117. [2]. VardaKahn, et al.Inhibition of mushroom tyrosinase by tropolone Phytochemistry. Volume 24, Issue 5, 1985, Pages 905-908 Chemical & Physical Properties Molecular Formula C7H6O2 Exact Mass 122.036781 PSA 37.30000 Index of Refraction 1.603 InChIKey MDYOLVRUBBJPFM-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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