CAS Number3262-64-4
Synonyms(R)-2-Amino-3-(2-propynylthio)propanoicAcid; (R)-2-Amino-3-(2-propynylthio)propanoic Acid; 2-amino-3-prop-2-ynylsulfanyl-propionic acid; S-propargyl cysteine; S-Prop-2-inyl-L-cystein; (R)-2-Amino-3-(prop-2-yn-1-ylthio)propanoic acid; S-2-Propinyl-L-cystein; S-prop-2-ynyl-L-cysteine; S-propargyl-L-cysteine
Molecular FormulaC6H9O2N1S1
Molecular Weight159.21
Density1.284g/cm3
Boiling Point294.8ºC at 760 mmHg
Melting Point176-178 °C
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3262-64-4 |
| Catalog No. | 2A-9088562 |
| Chinese Name | (R)-2-氨基-3-(2-丙炔基巯基)丙酸 |
| Synonyms | (R)-2-Amino-3-(2-propynylthio)propanoicAcid; (R)-2-Amino-3-(2-propynylthio)propanoic Acid; 2-amino-3-prop-2-ynylsulfanyl-propionic acid; S-propargyl cysteine; S-Prop-2-inyl-L-cystein; (R)-2-Amino-3-(prop-2-yn-1-ylthio)propanoic acid; S-2-Propinyl-L-cystein; S-prop-2-ynyl-L-cysteine; S-propargyl-L-cysteine |
| Molecular Formula | C6H9O2N1S1 |
| Molecular Weight | 159.21 |
| Density | 1.284g/cm3 |
| Boiling Point | 294.8ºC at 760 mmHg |
| Melting Point | 176-178 °C |
| Storage Condition | Room temperature, sealed, dry |
| Application | S-Propargylcysteine (SPRC) is a structural analog of S-allylcysteine (SAC), a slowly releasing H2S compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits ST |
| HTC | 2930909090 |
| MDL Number | MFCD06809960 |
| SMILES | C#CCSCC(N)C(=O)O |
| InChI Key | JAKVEOCMEMGHGB-YFKPBYRVSA-N |
| MSDS | msds/88562_1_3262_64_4.pdf |
| Use of | S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2]. Properties Name (2R)-2-amino-3-prop-2-ynylsulfanylpropanoic acid Synonym More Synonyms Biological Activity Description S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H2S-releasing compound. S-Propargylcysteine reduces Ca2+ accumulation and inflammatory cytokines, inhibits STAT3, and elevates p53 and Bax. S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties[1][2]. Related Catalog Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Inflammation/Immunology References [1]. Sidhapuriwala JN, et al. Effects of S-propargyl-cysteine (SPRC) in caerulein-induced acute pancreatitis in mice. PLoS One. 2012;7(3):e32574. [2]. Wen YD, et al. The Pharmacological Effects of S-Propargyl-Cysteine, a Novel Endogenous H2S-Producing Compound. Handb Exp Pharmacol. 2015;230:325-36. Chemical & Physical Properties Molecular Formula C6H9NO2S Exact Mass 159.03500 PSA 88.62000 LogP 0.46500 Index of Refraction 1.57 InChIKey JAKVEOCMEMGHGB-YFKPBYRVSA-N SMILES C#CCSCC(N)C(=O)O Safety Information Hazard Codes Xi HS Code 2930909090 Precursor & DownStream Precursor 4 CAS#:52-89-1 L-Cysteine hydr... CAS#:106-96-7 3-Bromopropyne CAS#:52-90-4 L-cysteine CAS#:624-65-7 3-Chloropropyne DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2930909090. other organo-sulfur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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