CAS Number57-88-5
Synonyms20-Dihydro-11-deoxycortisol; cholesterin; D5-Cholesten-3b-ol; 20-Dihydro Cortexolone; 3b-Hydroxy-5-cholestene; 5:6-Cholesten-3b-ol; (3β)-Cholest-5-en-3-ol; δ5-Cholesten-3β-ol; Cholest-5-en-3-ol (3β)-; Cholest-5-en-3b-ol; EINECS 200-353-2; 5-Cholesten-3B-ol; 5-Cholesten-3β-ol; Cholesterol; (3b)-cholest-5-en-3-ol; 3β-Hydroxycholest-5-ene; 5:6-Cholesten-3β-ol; 7α-Cholesterol; MFCD00003646; (-)-Cholesterol; Cholest-5-en-3β-ol
Molecular FormulaC27H46O
Molecular Weight386.65
Purity≥90.0 (GC)%
Density1.0±0.1 g/cm3
Boiling Point360 °C (lit.)
Melting Point147-149 °C (lit.)
AppearanceWhite crystalline solid
EINECS200-353-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 57-88-5 |
| Catalog No. | 2A-9008757 |
| Chinese Name | 胆固醇 |
| Synonyms | 20-Dihydro-11-deoxycortisol; cholesterin; D5-Cholesten-3b-ol; 20-Dihydro Cortexolone; 3b-Hydroxy-5-cholestene; 5:6-Cholesten-3b-ol; (3β)-Cholest-5-en-3-ol; δ5-Cholesten-3β-ol; Cholest-5-en-3-ol (3β)-; Cholest-5-en-3b-ol; EINECS 200-353-2; 5-Cholesten-3B-ol; 5-Cholesten-3β-ol; Cholesterol; (3b)-cholest-5-en-3-ol; 3β-Hydroxycholest-5-ene; 5:6-Cholesten-3β-ol; 7α-Cholesterol; MFCD00003646; (-)-Cholesterol; Cholest-5-en-3β-ol |
| Molecular Formula | C27H46O |
| Molecular Weight | 386.65 |
| Purity | ≥90.0 (GC) |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 360 °C (lit.) |
| Melting Point | 147-149 °C (lit.) |
| Appearance | White crystalline solid |
| Water Solubility | negligible |
| Storage Condition | 1. Store in a sealed container at 4ºC |
| Application | Cholesterol is the main steroid compound in mammals and plays an important role in basic cellular life activities. |
| EINECS | 200-353-2 |
| HTC | 2906131000 |
| MDL Number | MFCD00003646 |
| SMILES | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C |
| InChI | 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1 |
| InChI Key | HVYWMOMLDIMFJA-DPAQBDIFSA-N |
| Beilstein/REAXYS | 1915888 |
| UNSPSC | 41116107 |
| Hazard Symbols | 3.0 |
| Safety Description | S22;S24/25 |
| MSDS | msds/8757_1_57_88_5.pdf |
| Bioactivity | Cholesterol is the major sterol in mammals, and its importance in fundamental cellular processes is becoming more appreciated. IC50 value:Target:In vitro: GT1-7 hypothalamic cells subjected to cholesterol depletion in vitro produced 20-31% reductions in cellular cholesterol content, similar to the decrease in cholesterol synthesis observed in diabetes [1].In vivo: Related Catalog Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Others Natural Products >> Steroids Target Human Endogenous Metabolite References [1]. Laverdy OG, et al. Effects of glycemic control upon serum lipids and lipid transfers to HDL in patients with type 2 diabetes mellitus: novel findings in unesterified cholesterol status. Experimental and Clinical Endocrinology & Diabetes, 2015, 123(4):232-239 [2]. Sandy Huey-Jen Hsu, et al. Validation of the Estimation of Low-density LipoproteinCholesterol by the Modified Friedewald Equation in EthnicChinese Adults Living in Taiwan. Internal Medicine, 54: 2291-2297, 2015 [3]. Fukui K, et al. Effect of Cholesterol Reduction on Receptor Signaling in Neurons. J Biol Chem. 2015 Sep 14. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 360 ºC Melting Point 148-150 °C Molecular Formula C27H46O Molecular Weight 386.654 Flash Point 250 ºC Exact Mass 386.354858 PSA 20.23000 LogP 9.85 Vapour Pressure 0.0±2.7 mmHg at 25°C Index of Refraction 1.525 InChIKey HVYWMOMLDIMFJA-DPAQBDIFSA-N SMILES CC(C)CCCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C Water Solubility negligible |
| Use of | Cholesterol is the major sterol in mammals, and its importance in fundamental cellular processes is becoming more appreciated. IC50 value:Target:In vitro: GT1-7 hypothalamic cells subjected to cholesterol depletion in vitro produced 20-31% reductions in cellular cholesterol content, similar to the decrease in cholesterol synthesis observed in diabetes [1].In vivo: Properties Articles2620 Name cholesterol Synonym More Synonyms cholesterol Biological Activity Description Cholesterol is the major sterol in mammals, and its importance in fundamental cellular processes is becoming more appreciated. IC50 value:Target:In vitro: GT1-7 hypothalamic cells subjected to cholesterol depletion in vitro produced 20-31% reductions in cellular cholesterol content, similar to the decrease in cholesterol synthesis observed in diabetes [1].In vivo: Related Catalog Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Others Natural Products >> Steroids Human Endogenous Metabolite References [1]. Laverdy OG, et al. Effects of glycemic control upon serum lipids and lipid transfers to HDL in patients with type 2 diabetes mellitus: novel findings in unesterified cholesterol status. Experimental and Clinical Endocrinology & Diabetes, 2015, 123(4):232-239 [2]. Sandy Huey-Jen Hsu, et al. Validation of the Estimation of Low-density LipoproteinCholesterol by the Modified Friedewald Equation in EthnicChinese Adults Living in Taiwan. Internal Medicine, 54: 2291-2297, 2015 [3]. Fukui K, et al. Effect of Cholesterol Reduction on Receptor Signaling in Neurons. J Biol Chem. 2015 Sep 14. Chemical & Physical Properties Molecular Formula C27H46O Exact Mass 386.354858 PSA 20.23000 Index of Refraction 1.525 InChIKey HVYWMOMLDIMFJA-DPAQBDIFSA-N Water Solubility negligible |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Botanical Reference Standards | ||
|---|---|---|
| Luteolin-7-glucoside | 5373-11-5 | 2A-9008163 |
| Luteolin-7-glucuronide | 2A-108164 | 2A-9008164 |
| Luteolinidin chloride | 1154-78-5 | 2A-9008165 |
| Mesterolone | 1424-00-6 | 2A-9008193 |
| Saikosaponinc | 20874-52-6 | 2A-9008735 |
| Stilbene dicarboxylic acid chloride | 2A-108758 | 2A-9008758 |
| Tanshinone I | 568-73-0 | 2A-9008772 |
| Tanshinone IIB | 2A-108773 | 2A-9008773 |
| Tectochrysin | 520-28-5 | 2A-9008774 |
| (-)-Arctigenin | 7770-78-7 | 2A-9008920 |
| Browse all Botanical Reference Standards products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS