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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > (S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine
(S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine structure, CAS 185517-74-2

(S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine

CAS Number185517-74-2

Synonyms(S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine; (1S)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine (S)-Rasagiline S-(-)-N-Propargyl-1-aminoindan; N-PROPARGYL-1(S)-AMINOINDAN; S-PAI; TVP1022

Molecular FormulaC12H13N

Molecular Weight171.24

Purity≥98 (HPLC)%

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Cat. No.: 2A-9086546 Purity: ≥98 (HPLC)%
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Quality Control of [ 185517-74-2 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number185517-74-2
Catalog No.2A-9086546
Chinese Name(S)-Rasagiline
Synonyms(S)-N-(2-Propynyl)-2,3-dihydroinden-1-amine; (1S)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine (S)-Rasagiline S-(-)-N-Propargyl-1-aminoindan; N-PROPARGYL-1(S)-AMINOINDAN; S-PAI; TVP1022
Molecular FormulaC12H13N
Molecular Weight171.24
Purity≥98 (HPLC)
Appearance(Powder, Film or Oil)
Storage Condition2-8℃
ApplicationTVP1022 is the S-isomer of Rasagiline.
PubChem ID329825241
MDL NumberMFCD09029306
SMILESC#CCN[C@H]1CCc2ccccc12
InChI1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m0/s1
InChI KeyRUOKEQAAGRXIBM-LBPRGKRZSA-N
NACRES CodeNA.77
UNSPSC12352200
MSDSmsds/86546_1_185517_74_2.pdf
BioactivityTVP1022 is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. Related Catalog Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease References [1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69. [2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20. Chemical & Physical Properties Molecular Formula C12H13N Molecular Weight 171.23800 Exact Mass 171.10500 PSA 12.03000 LogP 2.28760 Vapour Pressure 0.000816mmHg at 25°C InChIKey RUOKEQAAGRXIBM-LBPRGKRZSA-N SMILES C#CCNC1CCc2ccccc21 Storage condition 2-8℃
Use ofTVP1022 is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. Properties Name (1S)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine Synonym More Synonyms TVP1022 Biological Activity Description TVP1022 is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. Related Catalog Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease References [1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69. [2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20. Chemical & Physical Properties Molecular Formula C12H13N Exact Mass 171.10500 PSA 12.03000 LogP 2.28760 InChIKey RUOKEQAAGRXIBM-LBPRGKRZSA-N Storage condition 2-8℃
Transport InfoProduct name: TVP1022
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