CAS Number18263-25-7
Synonyms2-bromopalmitate; 2-Bromopalmitic acid; UNII:7EI4G5X28Z; 2-bromopalmitate,(+-)-isomer; 2-bromo-hexadecanoic acid; Hexadecanoic acid,2-bromo; EINECS 242-137-0; MFCD00004215; bromopalmitic acid; 2-Bromohexadecanoic acid
Molecular FormulaC16H31BrO2
Molecular Weight335.32
Density1.1±0.1 g/cm3
Boiling Point403.4±18.0 °C at 760 mmHg
Melting Point52-54 °C
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 18263-25-7 |
| Catalog No. | 2A-9086435 |
| Chinese Name | 2-溴十六烷酸 |
| Synonyms | 2-bromopalmitate; 2-Bromopalmitic acid; UNII:7EI4G5X28Z; 2-bromopalmitate,(+-)-isomer; 2-bromo-hexadecanoic acid; Hexadecanoic acid,2-bromo; EINECS 242-137-0; MFCD00004215; bromopalmitic acid; 2-Bromohexadecanoic acid |
| Molecular Formula | C16H31BrO2 |
| Molecular Weight | 335.32 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 403.4±18.0 °C at 760 mmHg |
| Melting Point | 52-54 °C |
| Appearance | solid |
| Storage Condition | This product should be sealed and stored away from |
| Application | 2-Bromohexadecanoic acid (2-bromopropionic acid) can be converted into 2-bromopalmitic acid (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2- |
| HTC | 2915900090 |
| SMILES | O=C(O)C(Br)CCCCCCCCCCCCCC |
| InChI | InChI=1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19) |
| InChI Key | DPRAYRYQQAXQPE-UHFFFAOYSA-N |
| UNSPSC | 41116107 |
| Hazard Symbols | transportation |
| MSDS | msds/86435_1_18263_25_7.pdf |
| Bioactivity | 2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology References [1]. Hu L, et al. Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate. Cell Death Dis. 2020 Apr 24;11(4):281. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 403.4±18.0 °C at 760 mmHg Melting Point 52-54 °C Molecular Formula C16H31BrO2 Molecular Weight 335.32 Flash Point 197.8±21.2 °C Exact Mass 334.150726 PSA 37.30000 LogP 7.76 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.480 InChIKey DPRAYRYQQAXQPE-UHFFFAOYSA-N SMILES CCCCCCCCCCCCCCC(Br)C(=O)O |
| Use of | 2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. Properties Articles30 Name 2-bromohexadecanoic acid Synonym More Synonyms 2-bromohexadecanoic acid Biological Activity Description 2-Bromohexadecanoic acid (2-Bromopalmitic acid) can be converted to 2-bromopalmitate (2-BP). 2-BP is a palmitoylation inhibitor targeting DHHC (Asp-His-His-Cys) protein palmitoyltransferase. 2-BP inhibits palmitoylation of GSDME-C during pyroptosis and inhibits BAK/BAX-Caspase 3-GSDME pathway-mediated pyroptosis[1]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology References [1]. Hu L, et al. Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate. Cell Death Dis. 2020 Apr 24;11(4):281. Chemical & Physical Properties Molecular Formula C16H31BrO2 Exact Mass 334.150726 PSA 37.30000 Index of Refraction 1.480 InChIKey DPRAYRYQQAXQPE-UHFFFAOYSA-N SMILES CCCCCCCCCCCCCCC(Br)C(=O)O |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Imported food hygiene supervision and inspection S. Export food hygiene supervision and inspection M. Imported commodity inspection N. Exported commodity inspection |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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