CAS Number162558-52-3
Synonyms(6-Methoxyquinolinio)acetic acid ethyl ester bromide,MQAE; (6-Methoxyquinolinio)acetic acid ethyl ester bromide MQAE; ethyl 2-(6-methoxyquinolin-1-ium-1-yl)acetate,bromide; MQAE
Molecular FormulaC14H16BrNO3
Molecular Weight326.19
Purity≥97.0 (TLC)%
Melting Point177-179 °C (lit.)
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 162558-52-3 |
| Catalog No. | 2A-9085050 |
| Chinese Name | 解毒喹 |
| Synonyms | (6-Methoxyquinolinio)acetic acid ethyl ester bromide,MQAE; (6-Methoxyquinolinio)acetic acid ethyl ester bromide MQAE; ethyl 2-(6-methoxyquinolin-1-ium-1-yl)acetate,bromide; MQAE |
| Molecular Formula | C14H16BrNO3 |
| Molecular Weight | 326.19 |
| Purity | ≥97.0 (TLC) |
| Melting Point | 177-179 °C (lit.) |
| Appearance | solid |
| Storage Condition | -20℃ |
| Application | MQAE is a fluorescent chloride ion indicator that is more sensitive and selective than the 36Cl isotope tracing method and the microelectrode method. |
| HTC | 2933499090 |
| PubChem ID | 329757076 |
| MDL Number | MFCD00467854 |
| SMILES | [Br-].CCOC(=O)C[n+]1cccc2cc(OC)ccc12 |
| InChI | 1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1 |
| InChI Key | DSLLHVISNOIYHR-UHFFFAOYSA-M |
| NACRES Code | NA.32 |
| UNSPSC | 12352106 |
| Hazard Symbols | transportation |
| MSDS | msds/85050_1_162558_52_3.pdf |
| Bioactivity | MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others In Vitro Bath-applied to acute brain slices, MQAE provides high-quality labeling of neuronal cells and their processes[1]. MQAE fluorescence is adequate and comparable method for measuring cAMP-dependent chloride transport in individual cells[2]. MQAE can be used to measure intracellular chloride concentration in primary cultures of rat aortic smooth muscle cells (VSMC)[3]. References [1]. Kovalchuk Y, et al. Two-photon chloride imaging using MQAE in vitro and in vivo. Cold Spring Harb Protoc. 2012 Jul 1;2012(7):778-85. [2]. Andersson C, et al. Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence. Microsc Res Tech. 2002 Dec 15;59(6):531-5. [3]. Koncz C, et al. Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cells. Am J Physiol. 1994 Dec;267(6 Pt 2):H2114-23. Chemical & Physical Properties Melting Point 177-179ºC(lit.) Molecular Formula C14H16BrNO3 Molecular Weight 326.18600 Exact Mass 325.03100 PSA 39.41000 InChIKey DSLLHVISNOIYHR-UHFFFAOYSA-M SMILES CCOC(=O)C[n+]1cccc2cc(OC)ccc21.[Br-] Storage condition -20℃ |
| Use of | Properties Articles13 Name 1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide Synonym More Synonyms MQAE Biological Activity Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others In Vitro Bath-applied to acute brain slices, MQAE provides high-quality labeling of neuronal cells and their processes[1]. MQAE fluorescence is adequate and comparable method for measuring cAMP-dependent chloride transport in individual cells[2]. MQAE can be used to measure intracellular chloride concentration in primary cultures of rat aortic smooth muscle cells (VSMC)[3]. References [1]. Kovalchuk Y, et al. Two-photon chloride imaging using MQAE in vitro and in vivo. Cold Spring Harb Protoc. 2012 Jul 1;2012(7):778-85. [2]. Andersson C, et al. Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence. Microsc Res Tech. 2002 Dec 15;59(6):531-5. [3]. Koncz C, et al. Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cells. Am J Physiol. 1994 Dec;267(6 Pt 2):H2114-23. Chemical & Physical Properties Molecular Formula C14H16BrNO3 Exact Mass 325.03100 PSA 39.41000 InChIKey DSLLHVISNOIYHR-UHFFFAOYSA-M Storage condition -20℃ |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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