CAS Number306-07-0
SynonymsN-Benzyl-N-methylprop-2-yn-1-amine hydrochloride; MFCD00012492; pargyline hydrochloride; N-methyl-N-2-propynyl-benzenemethanamine,hydrochloride; N-methyl-N-benzylpropargylamine hydrochloride; Pargyline HCl; N-Methyl-N-propargylbenzylamine Hydrochloride; Benzyl-methyl-prop-2-inyl-amin,Hydrochlorid; benzyl-methyl-prop-2-ynyl-amine,hydrochloride; N-Benzyl-N-methyl-2-propyn-1-amine hydrochloride (1:1); Eutonyl-ten; N-Methyl-N-2-propynylbenzylamine hydrochloride; N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride (1:1); Pargyline chloride; Benzylmethylpropynylamine hydrochloride; N-methyl-N-propargylbenzylamine hydro-chloride; Methylbenzylpropynylamine hydrochloride; Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1); EINECS 206-175-1; Eutonyl; n-methyl-n-2-propynylbenzenemethanam
Molecular FormulaC6H5CH2N(CH3)CH2C≡CH·HCl
Molecular Weight195.69
Purity98 (TLC)%
Boiling Point228.4ºC at 760 mmHg
Melting Point160-163 °C (lit.)
Appearancepowder or crystals
EINECS206-175-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 306-07-0 |
| Catalog No. | 2A-9083792 |
| Chinese Name | 盐酸帕吉林 |
| Synonyms | N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride; MFCD00012492; pargyline hydrochloride; N-methyl-N-2-propynyl-benzenemethanamine,hydrochloride; N-methyl-N-benzylpropargylamine hydrochloride; Pargyline HCl; N-Methyl-N-propargylbenzylamine Hydrochloride; Benzyl-methyl-prop-2-inyl-amin,Hydrochlorid; benzyl-methyl-prop-2-ynyl-amine,hydrochloride; N-Benzyl-N-methyl-2-propyn-1-amine hydrochloride (1:1); Eutonyl-ten; N-Methyl-N-2-propynylbenzylamine hydrochloride; N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride (1:1); Pargyline chloride; Benzylmethylpropynylamine hydrochloride; N-methyl-N-propargylbenzylamine hydro-chloride; Methylbenzylpropynylamine hydrochloride; Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1); EINECS 206-175-1; Eutonyl; n-methyl-n-2-propynylbenzenemethanam |
| Molecular Formula | C6H5CH2N(CH3)CH2C≡CH·HCl |
| Molecular Weight | 195.69 |
| Purity | 98 (TLC) |
| Boiling Point | 228.4ºC at 760 mmHg |
| Melting Point | 160-163 °C (lit.) |
| Appearance | powder or crystals |
| Storage Condition | Seal and store at -20 ºC |
| Packaging | III |
| Application | Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO). |
| EINECS | 206-175-1 |
| PubChem ID | 24278153 |
| MDL Number | MFCD00012492 |
| SMILES | Cl[H].CN(CC#C)Cc1ccccc1 |
| InChI | 1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H |
| InChI Key | BCXCABRDBBWWGY-UHFFFAOYSA-N |
| Beilstein/REAXYS | 3699487 |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/83792_1_306_07_0.pdf |
| Bioactivity | Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. Related Catalog Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Cardiovascular Disease References [1]. Bianchi P, et al. A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J. 2005 Apr;19(6):641-3. [2]. Fuentes JA, et al. Central mediation of the antihypertensive effect of pargyline in spontaneously hypertensive rats. Eur J Pharmacol. 1979 Jul 15;57(1):21-7. [3]. Puig M, et al. Effect on the sympathetic nervous system of chronic treatment with pargyline and l-Dopa. J Pharmacol Exp Ther. 1972 Jul;182(1):130-4. Chemical & Physical Properties Boiling Point 228.4ºC at 760 mmHg Melting Point 160-163ºC Molecular Formula C11H14ClN Molecular Weight 195.689 Flash Point 83.9ºC Exact Mass 195.081482 PSA 3.24000 LogP 2.55360 InChIKey BCXCABRDBBWWGY-UHFFFAOYSA-N SMILES C#CCN(C)Cc1ccccc1.Cl |
| Use of | Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. Properties Articles32 Name N-benzyl-N-methylprop-2-yn-1-amine,hydrochloride Synonym More Synonyms pargyline hydrochloride Biological Activity Description Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. Related Catalog Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Cardiovascular Disease References [1]. Bianchi P, et al. A new hypertrophic mechanism of serotonin in cardiac myocytes: receptor-independent ROS generation. FASEB J. 2005 Apr;19(6):641-3. [2]. Fuentes JA, et al. Central mediation of the antihypertensive effect of pargyline in spontaneously hypertensive rats. Eur J Pharmacol. 1979 Jul 15;57(1):21-7. [3]. Puig M, et al. Effect on the sympathetic nervous system of chronic treatment with pargyline and l-Dopa. J Pharmacol Exp Ther. 1972 Jul;182(1):130-4. Chemical & Physical Properties Exact Mass 195.081482 PSA 3.24000 LogP 2.55360 InChIKey BCXCABRDBBWWGY-UHFFFAOYSA-N |
| Transport Info | Product name: Youjiangning |
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