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Home > Products > Personal Care & Cosmetics > Active Ingredients > Dihydrosphingosine
Dihydrosphingosine structure, CAS 3102-56-5

Dihydrosphingosine

CAS Number3102-56-5

SynonymsEINECS 212-116-0; DL-erythro-1,3-Dihydroxy-2-aminooctadecane,DL-erythro-2-Amino-1,3-octadecanediol,DL-Sphinganine; DL-erythro-1,3-Dihydroxy-2-aminooctadecane DL-erythro-2-Amino-1,3-octadecanediol DL-Sphinganine; DL-ERYTHRO-DIHYDROSPHINGOSINE; MFCD00079141

Molecular FormulaC18H39NO2

Molecular Weight301.51

Purity≥98%

Density0.927g/cm3

Boiling Point446.2ºC at 760 mmHg

Melting Point70-72ºC

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9083595 Purity: ≥98%
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Quality Control of [ 3102-56-5 ] Purity: ≥98% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number3102-56-5
Catalog No.2A-9083595
Chinese NameD,L-赤型-二氢鞘氨醇
SynonymsEINECS 212-116-0; DL-erythro-1,3-Dihydroxy-2-aminooctadecane,DL-erythro-2-Amino-1,3-octadecanediol,DL-Sphinganine; DL-erythro-1,3-Dihydroxy-2-aminooctadecane DL-erythro-2-Amino-1,3-octadecanediol DL-Sphinganine; DL-ERYTHRO-DIHYDROSPHINGOSINE; MFCD00079141
Molecular FormulaC18H39NO2
Molecular Weight301.51
Purity≥98
Density0.927g/cm3
Boiling Point446.2ºC at 760 mmHg
Melting Point70-72ºC
Appearancesolid
Water Solubilitychloroform/methanol (9:1): 20 mg/mL, clear, colorl
Storage ConditionSealed in a cool, dry environment at -20 ºC
ApplicationDL-red dihydrosphingosine is an effective inhibitor of PKC and phospholipase A2 (PLA2) [1][2].
HTC2922199090
PubChem ID24893744
MDL NumberMFCD07371371
SMILESOC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
InChI1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
InChI KeyOTKJDMGTUTTYMP-ZWKOTPCHSA-N
NACRES CodeNA.77
UNSPSC12352211
Hazard Symbolstransportation
MSDSmsds/83595_1_3102_56_5.pdf
BioactivityDL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2)[1][2]. Related Catalog Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Signaling Pathways >> TGF-beta/Smad >> PKC References [1]. R Chao, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267(33):23459-62. [2]. Hiroyuki Nakamura, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484(1):9-17. Chemical & Physical Properties Density 0.927g/cm3 Boiling Point 446.2ºC at 760 mmHg Melting Point 70-72ºC Molecular Formula C18H39NO2 Molecular Weight 301.50800 Flash Point 223.7ºC Exact Mass 301.29800 PSA 66.48000 LogP 4.84850 Appearance of Characters white Index of Refraction 1.477 InChIKey OTKJDMGTUTTYMP-QZTJIDSGSA-N SMILES CCCCCCCCCCCCCCCC(O)C(N)CO Storage condition −20°C Water Solubility chloroform/methanol (9:1): 20 mg/mL, clear, colorless to faintly yellow
Use ofDL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2)[1][2]. Properties Articles29 Name DL-erythro-Dihydrosphingosine Synonym More Synonyms D,L-erythro-Dihydrosphingosine Biological Activity Description DL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2)[1][2]. Related Catalog Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Signaling Pathways >> TGF-beta/Smad >> PKC References [1]. R Chao, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267(33):23459-62. [2]. Hiroyuki Nakamura, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484(1):9-17. Chemical & Physical Properties Molecular Formula C18H39NO2 Exact Mass 301.29800 PSA 66.48000 LogP 4.84850 Appearance of Characters white Index of Refraction 1.477 InChIKey OTKJDMGTUTTYMP-QZTJIDSGSA-N SMILES CCCCCCCCCCCCCCCC(O)C(N)CO
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 30.0%
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip.
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