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Home > Products > Pharmaceuticals & Life Science > API & Advanced Intermediates > (s)-(-)-Propranololhydrochloride
(s)-(-)-Propranololhydrochloride structure, CAS 4199-10-4

(s)-(-)-Propranololhydrochloride

CAS Number4199-10-4

Synonymsdl-propranololHClbp; PROPRANOLOL HCL; dl-propranolol hcl; dl-propranololhydrochloridebp; PENTAPROPANOLOLHYDROCHLORIDE; Sazetidine A dihydrochloride; DL-PROPRANOLOL HYDROCHLORIDE; EINECS 224-096-0; PROPANOLOL HYDROCHLORIDE; L-Propranololhydrochlorid; MFCD00064547

Molecular FormulaC16H22ClNO2

Molecular Weight295.80400

Purity

Density

Boiling Point434.9ºC at 760mmHg

Melting Point193-195ºC(lit.)

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9083214 Purity:
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Quality Control of [ 4199-10-4 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number4199-10-4
Catalog No.2A-9083214
Chinese Name(S)-(-)-普奈洛尔 盐酸盐
Synonymsdl-propranololHClbp; PROPRANOLOL HCL; dl-propranolol hcl; dl-propranololhydrochloridebp; PENTAPROPANOLOLHYDROCHLORIDE; Sazetidine A dihydrochloride; DL-PROPRANOLOL HYDROCHLORIDE; EINECS 224-096-0; PROPANOLOL HYDROCHLORIDE; L-Propranololhydrochlorid; MFCD00064547
Molecular FormulaC16H22ClNO2
Molecular Weight295.80400
Boiling Point434.9ºC at 760mmHg
Melting Point193-195ºC(lit.)
Appearancepowder
Water Solubilityethanol: 10 mg/mL
Storage Condition2-8°C
Application(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values ​​of -8.16, -9.08 and -6.93 for β1, β2, and β3 respectively. (S)-(-)-Propranolol hydrochloride can be used in
HTC2906199090
SMILESCC(C)NCC(O)COc1cccc2ccccc12.Cl
InChI KeyZMRUPTIKESYGQW-UQKRIMTDSA-N
Use of(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2]. Properties Name (s)-(-)-propranolol hydrochloride Synonym More Synonyms (S)-(-)-PROPRANOLOL HYDROCHLORIDE Biological Activity Description (S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Inflammation/Immunology log Kd: -8.16 (β1-adrenergic receptor) log Kd: -9.08 (β2-adrenergic receptor) log Kd: -6.93 (β3-adrenergic receptor)[1] References [1]. Jillian G Baker , et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22. Chemical & Physical Properties Exact Mass 295.13400 PSA 41.49000 LogP 3.77040 Appearance of Characters powder InChIKey ZMRUPTIKESYGQW-UQKRIMTDSA-N Safety Information Signal Word Warning Hazard Statements H302-H312-H332 Precautionary Statements P280 Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves Hazard Codes Xn: Harmful; Safety Phrases 36 RIDADR NONH for all modes of transport WGK Germany 3 HS Code 2906199090 Synthetic Route 16204-21-0 (S)-(-)-PROPRAN... Literature: Takahashi, Hisashi; Sakuraba, Shunji; Takeda, Hideo; Achiwa, Kazuo Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5876 - 5878 1-Naphthalenol (S)-Glycidyl no... 115314-14-2 isopropylamine (S)-(-)-PROPRAN... Literature: Kitaori, Kazuhiro; Furukawa, Yoshiro; Yoshimoto, Hiroshi; Otera, Junzo Tetrahedron, 1999 , vol. 55, # 50 p. 14381 - 14390 isopropylamine 213130-05-3 (S)-(-)-PROPRAN... Literature: Bredikhina; Savel'ev; Bredikhin Russian Journal of Organic Chemistry, 2002 , vol. 38, # 2 p. 213 - 219 Precursor & DownStream Precursor 8 CAS#:90-15-3 1-Naphthalenol CAS#:115314-14-2 (S)-Glycidyl no... CAS#:75-31-0 isopropylamine CAS#:4199-09-1 (S)-1-(isopropy... DownStream 0
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