![1-(1,3-Benzodioxol-5-yl)-N-[5-[(S)-(2-chlorophenyl)[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-2-thiazolyl]-cyclopropanecarboxamide structure, CAS 926664-32-6](/structures/100000/82707_3_926664_32_6.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 926664-32-6 |
| Catalog No. | 2A-9082707 |
| Chinese Name | 1-(1,3-BENZODIOXOL-5-YL)-N-[5-[(S)-(2-CHLOROPHENYL)[(3R)-3-HYDROXY-1-PYRROLIDINYL]METHYL]-2-THIAZOLY |
| Molecular Formula | C25H24ClN3O4S |
| Molecular Weight | 497.99 |
| Density | 1.510±0.06 g/cm3 (20 °C, 760 mmHg) |
| Application | VRT-534 targets connexin 26 (Cx26). Vrt-534 showed dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. Vrt-534 can be used in rese |
| SMILES | O=C(Nc1ncc(C(c2ccccc2Cl)N2CCC(O)C2)s1)C1(c2ccc3c(c2)OCO3)CC1 |
| InChI Key | OUGLISSDQZYBGK-UHFFFAOYSA-N |
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