CAS Number708-53-2
Synonyms1-acetyl-2,3-dihydroxy-4-methoxybenzene; MFCD00180772; 1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone; 1-(2,3-DIHYDROXY-4-METHOXYPHENYL)-ETHANONE
Molecular FormulaC9H10O4
Molecular Weight182.17 (anhydrous basis)
Purity97%
Density1.3±0.1 g/cm3
Boiling Point359.6±42.0 °C at 760 mmHg
Melting Point125-130 °C
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 708-53-2 |
| Catalog No. | 2A-9081684 |
| Chinese Name | 2',3'-二羟基-4'-甲氧基苯乙酮 |
| Synonyms | 1-acetyl-2,3-dihydroxy-4-methoxybenzene; MFCD00180772; 1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone; 1-(2,3-DIHYDROXY-4-METHOXYPHENYL)-ETHANONE |
| Molecular Formula | C9H10O4 |
| Molecular Weight | 182.17 (anhydrous basis) |
| Purity | 97 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 359.6±42.0 °C at 760 mmHg |
| Melting Point | 125-130 °C |
| Appearance | solid |
| Storage Condition | room temperature, dry |
| Application | 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from paniculata. 2,3-Dihydroxy-4-methoxyacetophenone can improve cognitive function and has potential for use in Alzheimer's disease r |
| HTC | 2914509090 |
| PubChem ID | 329763041 |
| MDL Number | MFCD00180772 |
| SMILES | O.COc1ccc(C(C)=O)c(O)c1O |
| InChI | 1S/C9H10O4.H2O/c1-5(10)6-3-4-7(13-2)9(12)8(6)11;/h3-4,11-12H,1-2H3;1H2 |
| InChI Key | LLNNBEWBUXDRMW-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/81684_1_708_53_2.pdf |
| Bioactivity | 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease In Vitro 2,3-Dihydroxy-4-methoxyacetophenone protects HT22 cells on glutamate induced cell-death in a dose-dependent manner (EC50=10.94 μM). 2,3-Dihydroxy-4-methoxyacetophenone inhibits [Ca2+] accumulation in HT22 cells and has antioxidantive activity[1]. In Vivo 2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1]. References [1]. Jin Bae Weon, et al. The Ameliorating Effects of 2,3-dihydroxy-4-methoxyacetophenone on Scopolamine-Induced Memory Impairment in Mice and Its Neuroprotective Activity. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6732-6. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 359.6±42.0 °C at 760 mmHg Melting Point 133ºC Molecular Formula C9H10O4 Molecular Weight 182.173 Flash Point 147.7±21.4 °C Exact Mass 182.057907 PSA 66.76000 LogP 1.81 Vapour Pressure 0.0±0.8 mmHg at 25°C Index of Refraction 1.573 InChIKey VCONERRCKOKCHE-UHFFFAOYSA-N SMILES COc1ccc(C(C)=O)c(O)c1O |
| Use of | 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1]. Properties Name 1-(2,3-dihydroxy-4-methoxyphenyl)ethanone Synonym More Synonyms 2',3'-Dihydroxy-4'-methoxyacetophenone Biological Activity Description 2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound from Cynenchum paniculatum. 2,3-Dihydroxy-4-methoxyacetophenone improves cognitive function and may has the potential for the treatment of Alzheimer's disease research[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Jin Bae Weon, et al. The Ameliorating Effects of 2,3-dihydroxy-4-methoxyacetophenone on Scopolamine-Induced Memory Impairment in Mice and Its Neuroprotective Activity. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6732-6. Chemical & Physical Properties Molecular Formula C9H10O4 Exact Mass 182.057907 PSA 66.76000 Index of Refraction 1.573 InChIKey VCONERRCKOKCHE-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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