CAS Number4386-25-8
Synonyms2,2',4'-TRIHYDROXY-5-CHLOROAZOBENZENE-3-SULFONIC ACID; Lumohallion IREA; LuMogallion ,Ga and other Metals]; 2-hydroxy-3-sulfo-5-chlorobenzenazoresorcinol; LUMOGALLION; 4-Chloro-6-(2,4-dihydroxyphenylazo)-1-phenol-2-sulfonic Acid; 2,2',4'-Trihydroxy-5-chloroazobenzene-3-sulfonic Acid; 2,2,4-Trihydroxy-5-Chloroazobenzene-3-Sulfonic Acid
Molecular FormulaC12H9O6N2Cl1S1
Molecular Weight344.73
Density1.75g/cm3
AppearanceSolid;Orange to Amber to Dark red powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 4386-25-8 |
| Catalog No. | 2A-9080757 |
| Chinese Name | 荧光镓试剂 |
| Synonyms | 2,2',4'-TRIHYDROXY-5-CHLOROAZOBENZENE-3-SULFONIC ACID; Lumohallion IREA; LuMogallion ,Ga and other Metals]; 2-hydroxy-3-sulfo-5-chlorobenzenazoresorcinol; LUMOGALLION; 4-Chloro-6-(2,4-dihydroxyphenylazo)-1-phenol-2-sulfonic Acid; 2,2',4'-Trihydroxy-5-chloroazobenzene-3-sulfonic Acid; 2,2,4-Trihydroxy-5-Chloroazobenzene-3-Sulfonic Acid |
| Molecular Formula | C12H9O6N2Cl1S1 |
| Molecular Weight | 344.73 |
| Density | 1.75g/cm3 |
| Appearance | Solid;Orange to Amber to Dark red powder to crystal |
| Water Solubility | Water solubility: slightly soluble; soluble in: ac |
| Storage Condition | Store at room temperature, away from light, in a v |
| Application | Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. The excitation wavelength of Lumogallion is 490nm, the emission spectrum ranges from 520n |
| MDL Number | MFCD00047770 |
| SMILES | O=S(=O)(O)c1cc(Cl)cc(N=Nc2ccc(O)cc2O)c1O |
| InChI | InChI=1S/C12H9ClN2O6S/c13-6-3-9(12(18)11(4-6)22(19,20)21)15-14-8-2-1-7(16)5-10(8)17/h1-5,15,17-18H,(H,19,20,21)/b14-8- |
| InChI Key | OTKYOGBGHUUFPC-UHFFFAOYSA-N |
| MSDS | msds/80757_1_4386_25_8.pdf |
| Bioactivity | Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vitro Lumogallion (1 mM, 45 min) can be used to detect aluminum levels in brain tissue of Alzheimer's patients[1]. Lumogallion can be used as a probe to stain live cells with intracellular aluminum adjuvant[2]. Lumogallion (10 μM, 60 min) can be used to detect aluminum content in root tip cell tissue of plants[3]. Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Dissolved lumogallion in 0.1 M acetate buffer (pH 5.2). 2. Sample and 10 μM lumogallion were co-incubated for 60 min in the dark. 3. Washed the mixed sample well with acetate buffer solution twice, 15 minutes each, and observed under a confocal laser microscope. 4. Excitation wavelength is 488 nm , emission wavelength is 520 nm. References [1]. Ambreen Mirza, et al. The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy. J Alzheimers Dis. 2016 Oct 18;54(4):1333-1338. [2]. Irene Mile, et al. Al adjuvants can be tracked in viable cells by lumogallion staining. J Immunol Methods. 2015 Jul;422:87-94. [3]. Tatsuhiko Kataoka, et al. Highly sensitive analytical method for aluminum movement in soybean root through lumogallion staining. J. Plant Res. 110, 305-309 (1997). Chemical & Physical Properties Density 1.75g/cm3 Molecular Formula C12H9ClN2O6S Molecular Weight 344.72800 Exact Mass 343.98700 PSA 148.16000 LogP 4.19970 Index of Refraction 1.706 InChIKey OTKYOGBGHUUFPC-UHFFFAOYSA-N SMILES O=S(=O)(O)c1cc(Cl)cc(N=Nc2ccc(O)cc2O)c1O |
| Use of | Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm[1][2]. Properties Name Lumogallion [Fluorimetric reagent for Al, Ga and other metals] Synonym More Synonyms Biological Activity Description Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Ambreen Mirza, et al. The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy. J Alzheimers Dis. 2016 Oct 18;54(4):1333-1338. [2]. Irene Mile, et al. Al adjuvants can be tracked in viable cells by lumogallion staining. J Immunol Methods. 2015 Jul;422:87-94. [3]. Tatsuhiko Kataoka, et al. Highly sensitive analytical method for aluminum movement in soybean root through lumogallion staining. J. Plant Res. 110, 305-309 (1997). Chemical & Physical Properties Exact Mass 343.98700 PSA 148.16000 LogP 4.19970 Index of Refraction 1.706 InChIKey OTKYOGBGHUUFPC-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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