CAS Number56-57-5
SynonymsEINECS 200-281-1; MFCD00006738; 4-nitro-1-oxidoquinolin-1-ium; 4-nitroquinoline-N-oxide; Quinoline, 4-nitro-, 1-oxide; 4-Nitroquinoline 1-oxide; 4-nitroquinoline n-oxide
Molecular FormulaC9H6N2O3
Molecular Weight190.16
Purity≥98%
Density1.4±0.1 g/cm3
Boiling Point387.6±34.0 °C at 760 mmHg
Melting Point154-156 °C (lit.)
AppearanceYellow-brown crystal or powder
EINECS200-281-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 56-57-5 |
| Catalog No. | 2A-9080507 |
| Chinese Name | 4-硝基喹啉-N-氧化物 |
| Synonyms | EINECS 200-281-1; MFCD00006738; 4-nitro-1-oxidoquinolin-1-ium; 4-nitroquinoline-N-oxide; Quinoline, 4-nitro-, 1-oxide; 4-Nitroquinoline 1-oxide; 4-nitroquinoline n-oxide |
| Molecular Formula | C9H6N2O3 |
| Molecular Weight | 190.16 |
| Purity | ≥98 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 387.6±34.0 °C at 760 mmHg |
| Melting Point | 154-156 °C (lit.) |
| Appearance | Yellow-brown crystal or powder |
| Water Solubility | acetone: clear to hazy |
| Storage Condition | This product should be kept sealed. |
| Packaging | II |
| Application | Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage and induces cell apoptosis through the p53-dependent mitochondrial si |
| EINECS | 200-281-1 |
| PubChem ID | 57654464 |
| MDL Number | MFCD00006738 |
| SMILES | [O-][N+](=O)c1cc[n+]([O-])c2ccccc12 |
| InChI | 1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H |
| InChI Key | YHQDZJICGQWFHK-UHFFFAOYSA-N |
| Beilstein/REAXYS | 165756 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | 6.1 |
| MSDS | msds/80507_1_56_57_5.pdf |
| Bioactivity | Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Mukherjee A, et al. Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells. In Vivo. 2023 Mar-Apr;37(2):506-518. [2]. Han H, et al. 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. Toxicology. 2007 Feb 12;230(2-3):151-63. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 387.6±34.0 °C at 760 mmHg Melting Point 154-156 °C(lit.) Molecular Formula C9H6N2O3 Molecular Weight 190.16 Flash Point 188.2±25.7 °C Exact Mass 190.037842 PSA 71.28000 LogP 0.92 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.659 InChIKey YHQDZJICGQWFHK-UHFFFAOYSA-N SMILES O=[N+]([O-])c1cc[n+]([O-])c2ccccc12 Storage condition −20°C Stability Stable. Hygroscopic, light-sensitive. Incompatible with strong oxidizing agents. Water Solubility acetone: clear to hazy |
| Use of | Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2]. Properties Articles60 Name 4-nitroquinoline N-oxide Synonym More Synonyms 4-Nitroquinoline 1-oxide Biological Activity Description Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Mukherjee A, et al. Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells. In Vivo. 2023 Mar-Apr;37(2):506-518. [2]. Han H, et al. 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. Toxicology. 2007 Feb 12;230(2-3):151-63. Chemical & Physical Properties Molecular Formula C9H6N2O3 Exact Mass 190.037842 PSA 71.28000 Index of Refraction 1.659 InChIKey YHQDZJICGQWFHK-UHFFFAOYSA-N Stability Stable. Hygroscopic, light-sensitive. Incompatible with strong oxidizing agents. Water Solubility acetone: clear to hazy |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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