CAS Number62-32-8
Synonyms4-[2-(Methylamino)ethyl]benzene-1,2-diol hydrochloride (1:1); Pyrocatechol, 4-[2- (methylamino)ethyl]-, hydrochloride; Ephinine hydrochloride; 1,2-Benzenediol, 4-[2-(methylamino)ethyl]-, hydrochloride (1:1); MFCD00035074; 1,2-Benzenediol, 4-[2-(methylamino)ethyl]-hydrochloride; 1,2-Benzenediol, 4-[2- (methylamino)ethyl]-, hydrochloride; N-Methyldopamine hydrochloride; 3,4-Dihydroxyphenylethylmethylamine hydrochloride; EPININE HCl; 3,4-dihydroxyphenethylmethylammonium chloride; Methyldopamine hydrochloride; EINECS 200-528-3; 4-[2-(Methylamino)ethyl]-1,2-benzenediol hydrochloride (1:1); Deoxyepinephrine hydrochloride; Epinine hydrochloride
Molecular FormulaC9H14ClNO2
Molecular Weight203.666
Boiling Point328.6ºC at 760 mmHg
Melting Point174-176ºC
Appearancesolid | white
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 62-32-8 |
| Catalog No. | 2A-9079968 |
| Chinese Name | N-甲基多巴胺 |
| Synonyms | 4-[2-(Methylamino)ethyl]benzene-1,2-diol hydrochloride (1:1); Pyrocatechol, 4-[2- (methylamino)ethyl]-, hydrochloride; Ephinine hydrochloride; 1,2-Benzenediol, 4-[2-(methylamino)ethyl]-, hydrochloride (1:1); MFCD00035074; 1,2-Benzenediol, 4-[2-(methylamino)ethyl]-hydrochloride; 1,2-Benzenediol, 4-[2- (methylamino)ethyl]-, hydrochloride; N-Methyldopamine hydrochloride; 3,4-Dihydroxyphenylethylmethylamine hydrochloride; EPININE HCl; 3,4-dihydroxyphenethylmethylammonium chloride; Methyldopamine hydrochloride; EINECS 200-528-3; 4-[2-(Methylamino)ethyl]-1,2-benzenediol hydrochloride (1:1); Deoxyepinephrine hydrochloride; Epinine hydrochloride |
| Molecular Formula | C9H14ClNO2 |
| Molecular Weight | 203.666 |
| Boiling Point | 328.6ºC at 760 mmHg |
| Melting Point | 174-176ºC |
| Appearance | solid | white |
| Water Solubility | H2O: soluble |
| Storage Condition | 2-8°C |
| Application | N-methyldopamine hydrochloride is the precursor of epinephrine in the adrenal medulla. N-methyldopamine hydrochloride is a modification of dopamine (DA) and retains agonist activity at the DA1 recepto |
| HTC | 2922299090 |
| PubChem ID | 572298 |
| SMILES | CNCCc1ccc(O)c(O)c1.Cl |
| InChI | InChI=1S/C9H13NO2.ClH/c1-10-5-4-7-2-3-8(11)9(12)6-7;/h2-3,6,10-12H,4-5H2,1H3;1H |
| InChI Key | JCDRZCWRRLKLTB-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research[1][2][3]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Target D1 Receptor In Vitro N-Methyldopamine hydrochloride shows highly improved surface coating properties, and exhibits an accelerated coating rate. N-Methyldopamine hydrochloride coating makes solid surface cell adhesion possible, and postfunctionalization of the coating is also possible[1]. References [1]. Kim Y, et al. Effect of N-Methylation on Dopamine Surface Chemistry. Langmuir. 2022 May 24;38(20):6404-6410. [2]. Laduron P. N-Methyldopamine (epinine), a precursor of adrenaline in the adrenal medulla. Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196:304-. [3]. Rajfer SI, et al. Effects of long-term therapy with oral ibopamine on resting hemodynamics and exercise capacity in patients with heart failure: relationship to the generation of N-methyldopamine and to plasma norepinephrine levels. Circulation. 1986 Apr;73(4):740-8. Chemical & Physical Properties Boiling Point 328.6ºC at 760 mmHg Melting Point 174-176ºC Molecular Formula C9H14ClNO2 Molecular Weight 203.666 Flash Point 154.3ºC Exact Mass 203.071304 PSA 52.49000 LogP 2.05260 Appearance of Characters solid | white InChIKey JCDRZCWRRLKLTB-UHFFFAOYSA-N SMILES CNCCc1ccc(O)c(O)c1.Cl Storage condition 2-8°C Water Solubility H2O: soluble |
| Use of | N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research[1][2][3]. Properties Name 4-[2-(methylamino)ethyl]benzene-1,2-diol,hydrochloride Synonym More Synonyms n-methyldopamine hydrochloride Biological Activity Description N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research[1][2][3]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease D1 Receptor In Vitro N-Methyldopamine hydrochloride shows highly improved surface coating properties, and exhibits an accelerated coating rate. N-Methyldopamine hydrochloride coating makes solid surface cell adhesion possible, and postfunctionalization of the coating is also possible[1]. References [1]. Kim Y, et al. Effect of N-Methylation on Dopamine Surface Chemistry. Langmuir. 2022 May 24;38(20):6404-6410. [2]. Laduron P. N-Methyldopamine (epinine), a precursor of adrenaline in the adrenal medulla. Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196:304-. [3]. Rajfer SI, et al. Effects of long-term therapy with oral ibopamine on resting hemodynamics and exercise capacity in patients with heart failure: relationship to the generation of N-methyldopamine and to plasma norepinephrine levels. Circulation. 1986 Apr;73(4):740-8. Chemical & Physical Properties Exact Mass 203.071304 PSA 52.49000 LogP 2.05260 Appearance of Characters solid | white InChIKey JCDRZCWRRLKLTB-UHFFFAOYSA-N Water Solubility H2O: soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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