
CAS Number26016-99-9
Synonyms(−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid,Fosfomycin,Phosphomycin disodium salt; (1R,2S)-1,2-Epoxypropylphosphonic Acid Disodium Salt; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, sodium salt (1:2); Disodium fosfomycin; FosfomycinDisodiumSalt; Fosfomycin Sodium; Disodium (1R,2S)-1,2-Epoxypropylphosphonate; fosfomycin disodium; Disodium [(2R,3S)-3-methyloxiran-2-yl]phosphonate; MFCD00056853; EINECS 247-409-2; Phosphomycin Disodium Salt; Disodium [(2R,3S)-3-methyl-2-oxiranyl]phosphonate; Fosfomycin sodium salt; Sodium,(2S,3R)-3-methyloxiran-2-yl)phosphonate; Disodium phosphonomycin; Fosfomycin Disodium Salt
Molecular FormulaC3H5Na2O4P
Molecular Weight182.02
Purity98%
Boiling Point342.7ºC at 760 mmHg
Melting Point>300°C
AppearanceSolid;White to Almost white powder to crystal
EINECS247-409-2
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 26016-99-9 |
| Catalog No. | 2A-9007880 |
| Chinese Name | 磷霉素钠 |
| Synonyms | (−)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid,Fosfomycin,Phosphomycin disodium salt; (1R,2S)-1,2-Epoxypropylphosphonic Acid Disodium Salt; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, sodium salt (1:2); Disodium fosfomycin; FosfomycinDisodiumSalt; Fosfomycin Sodium; Disodium (1R,2S)-1,2-Epoxypropylphosphonate; fosfomycin disodium; Disodium [(2R,3S)-3-methyloxiran-2-yl]phosphonate; MFCD00056853; EINECS 247-409-2; Phosphomycin Disodium Salt; Disodium [(2R,3S)-3-methyl-2-oxiranyl]phosphonate; Fosfomycin sodium salt; Sodium,(2S,3R)-3-methyloxiran-2-yl)phosphonate; Disodium phosphonomycin; Fosfomycin Disodium Salt |
| Molecular Formula | C3H5Na2O4P |
| Molecular Weight | 182.02 |
| Purity | 98 |
| Boiling Point | 342.7ºC at 760 mmHg |
| Melting Point | >300°C |
| Appearance | Solid;White to Almost white powder to crystal |
| Water Solubility | H2O: 50 mg/mL, clear, colorless |
| Storage Condition | 2-8℃ |
| Application | Fosfomycin sodium (MK-0955 sodium) is a broad-spectrum antibiotic that can penetrate the blood-brain barrier and irreversibly inhibit the early stages of cell wall synthesis. Fosfomycin sodium has bac |
| EINECS | 247-409-2 |
| PubChem ID | 329754806 |
| MDL Number | MFCD22741288 |
| SMILES | [Na+].[Na+].C[C@@H]1O[C@@H]1P([O-])([O-])=O |
| InChI | 1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m0../s1 |
| InChI Key | QZIQJIKUVJMTDG-JSTPYPERSA-L |
| Beilstein/REAXYS | 4604425 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/7880_1_26016_99_9.pdf |
| Bioactivity | Fosfomycin sodium (MK-0955 sodium) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31;6(4). pii: E24. Chemical & Physical Properties Boiling Point 342.7ºC at 760 mmHg Melting Point >300°C Molecular Formula C3H5Na2O4P Molecular Weight 182.023 Exact Mass 181.972092 PSA 85.53000 LogP 0.78530 Vapour Pressure 1.34E-05mmHg at 25°C InChIKey QZIQJIKUVJMTDG-OTUWWBTESA-L SMILES CC1OC1P(=O)([O-])[O-].[Na+].[Na+] Storage condition 2-8°C Water Solubility H2O: 50 mg/mL, clear, colorless |
| Use of | Fosfomycin sodium (MK-0955 sodium) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1]. Properties Name Fosfomycin Disodium Salt Synonym More Synonyms Disodium phosphonomycin Biological Activity Description Fosfomycin sodium (MK-0955 sodium) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. Fosfomycin sodium shows both in vivo and in vitro activity against a wide range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial References [1]. Dijkmans AC, et al. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31;6(4). pii: E24. Chemical & Physical Properties Molecular Formula C3H5Na2O4P Exact Mass 181.972092 PSA 85.53000 LogP 0.78530 InChIKey QZIQJIKUVJMTDG-OTUWWBTESA-L SMILES CC1OC1P(=O)([O-])[O-].[Na+].[Na+] |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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