CAS Number1672-58-8
Synonyms4-formylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one; N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide; N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide; N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)carboxamide; (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imidoformic acid; 4-Formylaminoantipyrine; 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylformamide; 4-Formamidoantipyrine; Formamide,N-antipyrinyl; N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)formamide; 4-formyl-aminoantipyrin; 4-Formylaminoantipyrine (N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide; 4-formaminoantipyrine; N-Formyl-4-aminoantipyrine
Molecular FormulaC12H13N3O2
Molecular Weight231.25
Density1.2±0.1 g/cm3
Boiling Point374.5±52.0 °C at 760 mmHg
Melting Point189-192ºC
AppearanceSolid;White to Orange to Green powder to crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1672-58-8 |
| Catalog No. | 2A-9077940 |
| Chinese Name | 4-甲酰氨基-1,2-二氢-1,5-二甲基-2-苯基-3H-吡唑-3-酮 |
| Synonyms | 4-formylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one; N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide; N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide; N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)carboxamide; (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imidoformic acid; 4-Formylaminoantipyrine; 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylformamide; 4-Formamidoantipyrine; Formamide,N-antipyrinyl; N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)formamide; 4-formyl-aminoantipyrin; 4-Formylaminoantipyrine (N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide; 4-formaminoantipyrine; N-Formyl-4-aminoantipyrine |
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | 231.25 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 374.5±52.0 °C at 760 mmHg |
| Melting Point | 189-192ºC |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Storage Condition | Refrigerator |
| Application | 4-Formylaminoantipyrine is the excretory metabolite of aminobennarone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties. |
| HTC | 2933199090 |
| PubChem ID | 329817810 |
| SMILES | Cc1c(NC=O)c(=O)n(-c2ccccc2)n1C |
| InChI | InChI=1S/C12H13N3O2/c1-9-11(13-8-16)12(17)15(14(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3,(H,13,16) |
| InChI Key | WSJBSKRPKADYRQ-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1]. Related Catalog Research Areas >> Metabolic Disease References [1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther [2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31. [3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 374.5±52.0 °C at 760 mmHg Melting Point 189-192ºC Molecular Formula C12H13N3O2 Molecular Weight 231.251 Flash Point 180.3±30.7 °C Exact Mass 231.100784 PSA 56.03000 LogP 0.41 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.609 InChIKey WSJBSKRPKADYRQ-UHFFFAOYSA-N SMILES Cc1c(NC=O)c(=O)n(-c2ccccc2)n1C Storage condition Refrigerator |
| Use of | 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1]. Properties Articles19 Name 4-formylaminoantipyrine Synonym More Synonyms 4-Formamidoantipyrine Biological Activity Description 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1]. Related Catalog Research Areas >> Metabolic Disease References [1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther [2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31. [3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79. Chemical & Physical Properties Molecular Formula C12H13N3O2 Exact Mass 231.100784 PSA 56.03000 Index of Refraction 1.609 InChIKey WSJBSKRPKADYRQ-UHFFFAOYSA-N Storage condition Refrigerator |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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