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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > N-[4-(9-Chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide
N-[4-(9-Chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide structure, CAS 150683-30-0

N-[4-(9-Chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide

CAS Number150683-30-0

Synonyms(±)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide; Tolvaptan; UNII-21G72T1950; olvaptan; Samsca; benzazepine derivative,32

Molecular FormulaC26H25ClN2O3

Molecular Weight448.941

Purity98%%

Density1.3±0.1 g/cm3

Boiling Point594.4±50.0 °C at 760 mmHg

Melting Point219-222°C

Flash Point

Appearancewhite to tan

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Cat. No.: 2A-9077057 Purity: 98%%
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Quality Control of [ 150683-30-0 ] Purity: 98%% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number150683-30-0
Catalog No.2A-9077057
Chinese Name托伐普坦
Synonyms(±)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide; Tolvaptan; UNII-21G72T1950; olvaptan; Samsca; benzazepine derivative,32
Molecular FormulaC26H25ClN2O3
Molecular Weight448.941
Purity98%
Density1.3±0.1 g/cm3
Boiling Point594.4±50.0 °C at 760 mmHg
Melting Point219-222°C
Appearancewhite to tan
Water SolubilityDMSO: ≥15mg/mL
Storage ConditionRefrigerator
ApplicationTolvaptan is an arginine vasopressin receptor 2 antagonist that inhibits AVP-induced platelet aggregation with an IC50 of 1.28 μM.
PubChem ID9372812
SMILESCc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc32)c(C)c1
InChIInChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)/t24-/m1/s1
InChI KeyGYHCTFXIZSNGJT-UHFFFAOYSA-N
Transport InfoProduct Name: Tolvaptan
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