| Chemical & Physical Properties | |
|---|---|
| CAS Number | 107622-80-0 |
| Catalog No. | 2A-9076258 |
| Chinese Name | 4-苯氧基苄胺 |
| Synonyms | (4-Phenoxyphenyl)methanamine; MFCD01310836; 1-(4-Phenoxyphenyl)methanamine |
| Molecular Formula | C13H13NO |
| Molecular Weight | 199.25 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 319.6±25.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | room temperature |
| Application | 4-Phenoxybenzylamine inhibits the function of NS3 protein by stabilizing the inactive conformation, and the IC50 value for inhibiting FL NS3/4a is approximately 500 μM. |
| HTC | 2922299090 |
| PubChem ID | 329781356 |
| MDL Number | MFCD01310836 |
| SMILES | NCc1ccc(Oc2ccccc2)cc1 |
| InChI | 1S/C13H13NO/c14-10-11-6-8-13(9-7-11)15-12-4-2-1-3-5-12/h1-9H,10,14H2 |
| InChI Key | CCAZAGUSBMVSAR-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352116 |
| MSDS | msds/76258_1_107622_80_0.pdf |
| Use of | Properties Name 4-Phenoxybenzylamine Synonym More Synonyms 4-Phenoxybenzylamine Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection In Vitro A highly conserved novel binding site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein is identified. 4-Phenoxybenzylamine binding at this allosteric site inhibits the function of the NS3 protein by stabilizing an inactive conformation and thus represents a new class of direct acting antiviral agents[1]. References [1]. Saalau-Bethell SM, et al. Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function. Nat Chem Biol. 2012 Nov;8(11):920-5. Chemical & Physical Properties Molecular Formula C13H13NO Exact Mass 199.099716 PSA 35.25000 Index of Refraction 1.595 InChIKey CCAZAGUSBMVSAR-UHFFFAOYSA-N Safety Information Hazard Codes C: Corrosive;Xi: Irritant; HS Code 2922299090 Synthetic Route 4-Phenoxybenzon... CAS#:3096-81-9 4-Phenoxybenzylamine CAS#:107622-80-0 Literature: Fotsch; Sonnenberg; Chen; Hale; Karbon; Norman Journal of Medicinal Chemistry, 2001 , vol. 44, # 14 p. 2344 - 2356 4-Fluorobenzonitrile CAS#:1194-02-1 4-Phenoxybenzylamine CAS#:107622-80-0 Literature: Journal of Medicinal Chemistry, , vol. 44, # 14 p. 2344 - 2356 CAS#:108-95-2 4-Phenoxybenzylamine CAS#:107622-80-0 Literature: Journal of Medicinal Chemistry, , vol. 44, # 14 p. 2344 - 2356 Precursor & DownStream Precursor 7 CAS#:3096-81-9 4-Phenoxybenzon... CAS#:1194-02-1 4-Fluorobenzonitrile CAS#:108-95-2 CAS#:2215-77-2 4-Phenoxybenzoi... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 3-Amino-2-bromo-benzoicacidmethylester | 106896-48-4 | 2A-9076222 |
| 2,3-Epoxypropylacrylate | 106-90-1 | 2A-9076223 |
| 1,3,2-Dioxathiolane-2,2-dioxide | 1072-53-3 | 2A-9076229 |
| 2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)aceticacid | 107367-98-6 | 2A-9076252 |
| 6-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine | 1076197-93-7 | 2A-9076257 |
| N-methyltaurine | 107-68-6 | 2A-9076259 |
| 4-Amino-3-bromopyridin-2-ol | 107842-74-0 | 2A-9076261 |
| 3,5-Dihydroxy-4-nitrobenzoicacid | 1081544-32-2 | 2A-9076263 |
| 3-(6-Amino-3-methyl-pyridin-2-yl)-benzoicacidtert-butylester | 1083057-14-0 | 2A-9076266 |
| Phenyl7-bromo-1-methoxy-3-Methyl-2-naphthoate | 1083181-76-3 | 2A-9076268 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS