| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1068-84-4 |
| Catalog No. | 2A-9076221 |
| Chinese Name | 氨基丙二酸 |
| Synonyms | Aminomalonic acid; 2-aminopropanedioic acid; aminopropanedioic acid |
| Molecular Formula | C3H5NO4 |
| Molecular Weight | 119.08 |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 402.6±40.0 °C at 760 mmHg |
| Melting Point | 240-245°C |
| Storage Condition | room temperature, dry |
| Application | Aminomalonic acid is an amino endogenous metabolite that acts as a highly potent inhibitor of L-asparagine synthase derived from Leukemia 5178Y/AR and mouse pancreas in vitro (Leukemia 5178Y/AR: Ki = |
| HTC | 2922499990 |
| PubChem ID | 4129 |
| SMILES | NC(C(=O)O)C(=O)O |
| InChI | InChI=1S/C3H5NO4/c4-1(2(5)6)3(7)8/h1H,4H2,(H,5,6)(H,7,8) |
| InChI Key | JINBYESILADKFW-UHFFFAOYSA-N |
| Use of | Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3]. Properties Name aminomalonic acid Synonym More Synonyms Aminomalonic acid Biological Activity Description Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3]. Related Catalog Research Areas >> Cancer Ki: 0.0023 M (L-asparagine synthetase from Leukemia 5178Y/AR), 0.0015 M (L-asparagine synthetase from mouse pancreas)[2] References [1]. Van Buskirk JJ, et al. Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Proc Natl Acad Sci U S A. 1984 Feb;81(3):722-5. [2]. Milman HA, et al. Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase. Enzyme. 1979;24(1):36-47. [3]. Kim HY, et al. Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling. Sci Rep. 2017 Aug 18;7(1):8864. Chemical & Physical Properties Molecular Formula C3H5NO4 Exact Mass 119.021858 PSA 100.62000 LogP -0.27 Index of Refraction 1.545 InChIKey JINBYESILADKFW-UHFFFAOYSA-N SMILES NC(C(=O)O)C(=O)O Safety Information Hazard Codes Xi HS Code 2922499990 Synthetic Route DL-Glutamic aci... Aminomalonic ac... DL-Aspartic Aci... Literature: Tetrahedron Letters, , vol. 24, # 44 p. 4839 - 4842 DL-Alanine Aminomalonic ac... (2S)-2-amino-3-... Literature: Tetrahedron Letters, , vol. 24, # 44 p. 4839 - 4842 DL-Methionine Aminomalonic ac... cysteic acid 13100-82-8 2-Amino-3-metha... 88547-35-7 Literature: Tetrahedron Letters, , vol. 24, # 44 p. 4839 - 4842 Precursor & DownStream Precursor 10 CAS#:40885-82-3 2-(2-PHENYLHYDR... CAS#:6829-41-0 DIETHYL ISONITR... CAS#:62009-47-6 2-Aminomalonamide CAS#:600-33-9 chloromalonic acid DownStream 3 CAS#:473-90-5 Oxomalonic acid CAS#:56-40-6 CAS#:55327-87-2 Acetamidomaloni... |
| Tax Rebate | 9.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | P. Quarantine of entry animals, plants, and animal and plant products Q. Quarantine of exit animals, plants, and animal and plant products R. Hygiene supervision and inspection of imported food S. Hyg |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 4-(1H-Imidazol-4(5)-yl)piperdine | 106243-23-6 | 2A-9076205 |
| 5-Ethynyl-2-methoxybenzonitrile | 1062617-60-0 | 2A-9076207 |
| 3-Fluoro-2-methoxybenzoicacid | 106428-05-1 | 2A-9076209 |
| 1-(4-(4-methyl-1H-imidazol-1-yl)phenyl)ethanone | 142161-53-3 | 2A-9076216 |
| 1-Pyridin-3-yl-1-tosylmethylisocyanide | 1067660-10-9 | 2A-9076218 |
| 3-Amino-2-bromo-benzoicacidmethylester | 106896-48-4 | 2A-9076222 |
| 2,3-Epoxypropylacrylate | 106-90-1 | 2A-9076223 |
| 1,3,2-Dioxathiolane-2,2-dioxide | 1072-53-3 | 2A-9076229 |
| 2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)aceticacid | 107367-98-6 | 2A-9076252 |
| 6-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine | 1076197-93-7 | 2A-9076257 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS