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4-Aminomethylbenzenesulfonamide

Name: 4-Aminomethylbenzenesulfonamide
Brand: 2A Biotech
SKU: 2A-9075067

CAS Number138-39-6

Synonyms4-(Aminomethyl)benzenesulfonamide; EINECS 205-326-9

Molecular FormulaC7H10N2O2S

Molecular Weight222.69

Purity≥95%

Density1.3±0.1 g/cm3

Boiling Point382.0±44.0 °C at 760 mmHg

Melting Point177-178℃ (decomposition)

EINECS205-325-3

MSDSChinese English

Cat. No.: 2A-9075067 Purity: ≥95%

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Quality Control of [ 138-39-6 ] Purity: ≥95% SDS Specification MoL

Chemical & Physical Properties
CAS Number	138-39-6
Catalog No.	2A-9075067
Chinese Name	磺胺米隆
Synonyms	4-(Aminomethyl)benzenesulfonamide; EINECS 205-326-9
Molecular Formula	C7H10N2O2S
Molecular Weight	222.69
Purity	≥95
Density	1.3±0.1 g/cm3
Boiling Point	382.0±44.0 °C at 760 mmHg
Melting Point	177-178℃ (decomposition)
Storage Condition	2-8℃
Application	Mafenide is a sulfonamide antibiotic.
EINECS	205-325-3
HTC	2935009090
PubChem ID	329770769
MDL Number	MFCD00013005
SMILES	Cl.NCc1ccc(cc1)S(N)(=O)=O
InChI	1S/C7H10N2O2S.ClH/c8-5-6-1-3-7(4-2-6)12(9,10)11;/h1-4H,5,8H2,(H2,9,10,11);1H
InChI Key	SIACJRVYIPXFKS-UHFFFAOYSA-N
NACRES Code	NA.24
UNSPSC	41116107
MSDS	msds/75067_1_138_39_6.pdf
Bioactivity	Mafenide is a sulfonamide-type medication.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 382.0±44.0 °C at 760 mmHg Melting Point 177-178℃ (decomposition) Molecular Formula C7H10N2O2S Molecular Weight 186.232 Flash Point 184.8±28.4 °C Exact Mass 186.046295 PSA 94.56000 LogP -0.80 Vapour Pressure 0.0±0.9 mmHg at 25°C Index of Refraction 1.602 InChIKey TYMRLRRVMHJFTF-UHFFFAOYSA-N SMILES NCc1ccc(S(N)(=O)=O)cc1 Storage condition 2-8℃
Use of	Mafenide is a sulfonamide-type medication.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Properties Name 4-Aminomethylbenzenesulfonamide Synonym More Synonyms Mafenide Biological Activity Description Mafenide is a sulfonamide-type medication.Target: AntibacterialMafenide is a sulfonamide-type medication. Mafenide works by reducing the bacterial population present in the avascular tissues of burns and permits spontaneous healing of deep partial-thickness burns. It is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns [1-3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9. Chemical & Physical Properties Molecular Formula C7H10N2O2S Exact Mass 186.046295 PSA 94.56000 LogP -0.80 Index of Refraction 1.602 InChIKey TYMRLRRVMHJFTF-UHFFFAOYSA-N Storage condition 2-8℃
Tax Rebate	9.0%
Supervision	None MFN tariff: 6.5% Ordinary tariff: 35.0%
Transport Info	Product name: Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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4-Aminomethylbenzenesulfonamide

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