CAS Number142253-56-3
Synonyms1-Boc-Azetidine-3-yl-methanol; tert-butyl 3-(hydroxymethyl)azetidine-1-carboxylate; 3-(Hydroxymethyl)azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-azetidinemethanol; 1-Boc-3-(hydroxymethyl)azetidine
Molecular FormulaC9H17NO3
Molecular Weight187.24
Density1.1±0.1 g/cm3
Boiling Point270.3±13.0 °C at 760 mmHg
Melting Point55 °C
AppearanceSolid;White to Almost white powder to lump
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 142253-56-3 |
| Catalog No. | 2A-9074560 |
| Chinese Name | 3-羟甲基氮杂环丁烷-1-羧酸叔丁酯 |
| Synonyms | 1-Boc-Azetidine-3-yl-methanol; tert-butyl 3-(hydroxymethyl)azetidine-1-carboxylate; 3-(Hydroxymethyl)azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-azetidinemethanol; 1-Boc-3-(hydroxymethyl)azetidine |
| Molecular Formula | C9H17NO3 |
| Molecular Weight | 187.24 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 270.3±13.0 °C at 760 mmHg |
| Melting Point | 55 °C |
| Appearance | Solid;White to Almost white powder to lump |
| Water Solubility | Soluble in Dimethyl sulfoxide (DMSO). |
| Storage Condition | Store under inert gas; avoid air |
| Application | 1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody drug conjugates (ADC). 1-Boc-azetidine-3-yl-methanol is also an alkyl chain-based PROTAC linker and can be |
| HTC | 2933990090 |
| PubChem ID | 15612197 |
| SMILES | CC(C)(C)OC(=O)N1CC(CO)C1 |
| InChI | InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3 |
| InChI Key | HXRDRJKAEYHOBB-UHFFFAOYSA-N |
| Bioactivity | Chemical & Physical Properties |
| Use of | 1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1] Properties Biological Activity Chemical & Physical Properties |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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