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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > (2R,4S)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylicacid
(2R,4S)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylicacid structure, CAS 147266-92-0

(2R,4S)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylicacid

CAS Number147266-92-0

Synonyms(4S)-4-Hydroxy-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline; Boc-trans-4-Hydroxy-D-proline; N-Boc-trans-4-hydroxy-D-proline; MFCD01861341

Molecular FormulaC10H17NO5

Molecular Weight231.25

Purity97%

Density1.3±0.1 g/cm3

Boiling Point390.9±42.0 °C at 760 mmHg

Melting Point119-125 °C

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9073496 Purity: 97%
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Quality Control of [ 147266-92-0 ] Purity: 97% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number147266-92-0
Catalog No.2A-9073496
Chinese NameN-BOC-反式-4-羟基-D-脯氨酸
Synonyms(4S)-4-Hydroxy-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline; Boc-trans-4-Hydroxy-D-proline; N-Boc-trans-4-hydroxy-D-proline; MFCD01861341
Molecular FormulaC10H17NO5
Molecular Weight231.25
Purity97
Density1.3±0.1 g/cm3
Boiling Point390.9±42.0 °C at 760 mmHg
Melting Point119-125 °C
Appearancesolid
Storage ConditionStorage method: dry, cool, airtight place
ApplicationN-tert-butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker for the synthesis of antibody-drug conjugates (ADC). N-tert-butoxycarbonyl-trans-4-hydroxy-D-proline is also an alkyl chai
HTC2933990090
PubChem ID329766602
MDL NumberMFCD23135644
SMILESCC(C)(C)OC(=O)N1C[C@@H](O)CC1C(O)=O
InChI1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7?/m0/s1
InChI KeyBENKAPCDIOILGV-PKPIPKONSA-N
NACRES CodeNA.22
UNSPSC12352209
Hazard Symbolstransportation
MSDSmsds/73496_1_147266_92_0.pdf
BioactivityChemical & Physical Properties
Use ofN-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]. Properties Biological Activity Chemical & Physical Properties
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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