CAS Number128117-22-6
Synonyms1-Cbz-3-Hydroxyazetidine; 1-Azetidinecarboxylic acid,3-hydroxy-,phenylmethyl ester; 1-Azetidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester
Molecular FormulaC11H13NO3
Molecular Weight207.23
Density1.3±0.1 g/cm3
Boiling Point356.7±42.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 128117-22-6 |
| Catalog No. | 2A-9072386 |
| Chinese Name | 1-苄氧羰基-3-羟基氮杂环丁烷 |
| Synonyms | 1-Cbz-3-Hydroxyazetidine; 1-Azetidinecarboxylic acid,3-hydroxy-,phenylmethyl ester; 1-Azetidinecarboxylic acid, 3-hydroxy-, phenylmethyl ester |
| Molecular Formula | C11H13NO3 |
| Molecular Weight | 207.23 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 356.7±42.0 °C at 760 mmHg |
| Storage Condition | 2-8°C |
| Application | 1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody drug conjugates (ADC). 1-Cbz-3-Hydroxyazetidine is also a PROTAC linker based on an alkyl chain and can be used |
| PubChem ID | 15067823 |
| SMILES | O=C(OCc1ccccc1)N1CC(O)C1 |
| InChI | InChI=1S/C11H13NO3/c13-10-6-12(7-10)11(14)15-8-9-4-2-1-3-5-9/h1-5,10,13H,6-8H2 |
| InChI Key | XJWSNDGCJMGHSR-UHFFFAOYSA-N |
| Bioactivity | Chemical & Physical Properties |
| Use of | 1-Cbz-3-Hydroxyazetidine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 1-Cbz-3-Hydroxyazetidine is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Properties Biological Activity Chemical & Physical Properties |
| Transport Info | Product name: 1-benzyloxycarbonyl-3-hydroxyazetidine |
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