CAS Number1571-30-8
Synonyms8-hydroxyquinoline-2-carboxylic acid; 8-Hydroxy-2-quinolinecarboxylic acid; MFCD00168972; 8-Hydroxyquinaldic acid
Molecular FormulaC10H7NO3
Molecular Weight189.17
Purity≥98.0 (HPLC)%
Density1.5±0.1 g/cm3
Boiling Point426.7±30.0 °C at 760 mmHg
Melting Point213-214 °C
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1571-30-8 |
| Catalog No. | 2A-9069877 |
| Chinese Name | 8-羟基喹啉-2-羧酸 |
| Synonyms | 8-hydroxyquinoline-2-carboxylic acid; 8-Hydroxy-2-quinolinecarboxylic acid; MFCD00168972; 8-Hydroxyquinaldic acid |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.17 |
| Purity | ≥98.0 (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 426.7±30.0 °C at 760 mmHg |
| Melting Point | 213-214 °C |
| Appearance | solid |
| Storage Condition | Keep container sealed and store in a cool, dry pla |
| Application | BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 does not affect NF-κB activation induced by doxorubicin (HY-15142A) [1]. |
| HTC | 2933499090 |
| PubChem ID | 57651493 |
| MDL Number | MFCD00168972 |
| SMILES | OC(=O)c1ccc2cccc(O)c2n1 |
| InChI | 1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14) |
| InChI Key | UHBIKXOBLZWFKM-UHFFFAOYSA-N |
| Beilstein/REAXYS | 146082 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/69877_1_1571_30_8.pdf |
| Bioactivity | BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1]. Related Catalog Signaling Pathways >> NF-κB >> IKK Research Areas >> Cancer Target IKK-α:60 nM (IC50) In Vitro BAY32-5915 (50-200 μM) has no significant inhibitory effect on NF-κB activity in melanoma cells[1]. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 426.7±30.0 °C at 760 mmHg Melting Point 213-214 °C Molecular Formula C10H7NO3 Molecular Weight 189.167 Flash Point 211.9±24.6 °C Exact Mass 189.042587 PSA 70.42000 LogP 1.96 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.730 InChIKey UHBIKXOBLZWFKM-UHFFFAOYSA-N SMILES O=C(O)c1ccc2cccc(O)c2n1 |
| Use of | BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1]. Properties Name 8-hydroxyquinoline-2-carboxylic acid Synonym More Synonyms 8-Hydroxyquinoline-2-Carboxylic Acid Biological Activity Description BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1]. Related Catalog Signaling Pathways >> NF-κB >> IKK Research Areas >> Cancer IKK-α:60 nM (IC50) In Vitro BAY32-5915 (50-200 μM) has no significant inhibitory effect on NF-κB activity in melanoma cells[1]. Chemical & Physical Properties Molecular Formula C10H7NO3 Exact Mass 189.042587 PSA 70.42000 Index of Refraction 1.730 InChIKey UHBIKXOBLZWFKM-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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