CAS Number575-03-1
Synonyms7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one; 7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one; 7-hydroxy-4-(trifluoromethyl)chromen-2-one; MFCD00037578
Molecular FormulaC10H5F3O3
Molecular Weight283.20
Purity98%
Density1.6±0.1 g/cm3
Boiling Point311.4±42.0 °C at 760 mmHg
Melting Point222-224 °C (dec.) (lit.)
AppearanceOff-white to light yellow or pink powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 575-03-1 |
| Catalog No. | 2A-9006971 |
| Chinese Name | 7-羟基-4-三氟甲基香豆素 |
| Synonyms | 7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one; 7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one; 7-hydroxy-4-(trifluoromethyl)chromen-2-one; MFCD00037578 |
| Molecular Formula | C10H5F3O3 |
| Molecular Weight | 283.20 |
| Purity | 98 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 311.4±42.0 °C at 760 mmHg |
| Melting Point | 222-224 °C (dec.) (lit.) |
| Appearance | Off-white to light yellow or pink powder |
| Water Solubility | DMF: soluble |
| Storage Condition | Storage: Seal the container and store it in a seal |
| Application | 4-(Trifluoromethyl)umbelliferone is a fluorescent probe substrate for rat liver cytochrome P450 enzyme [1]. |
| HTC | 2932209090 |
| PubChem ID | 24880283 |
| MDL Number | MFCD03701560 |
| SMILES | FC(F)(F)C1=CC(=O)Oc2cc(NC(=O)C=C)ccc12 |
| InChI | 1S/C13H8F3NO3/c1-2-11(18)17-7-3-4-8-9(13(14,15)16)6-12(19)20-10(8)5-7/h2-6H,1H2,(H,17,18) |
| InChI Key | WJZFVBAYCVHWRE-UHFFFAOYSA-N |
| NACRES Code | NA.23 |
| UNSPSC | 12352103 |
| Hazard Symbols | Transport |
| MSDS | msds/6971_1_575_03_1.pdf |
| Bioactivity | 4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Others References [1]. Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31(12):861-78. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 311.4±42.0 °C at 760 mmHg Melting Point 178-180 °C(lit.) Molecular Formula C10H5F3O3 Molecular Weight 230.140 Flash Point 142.2±27.9 °C Exact Mass 230.019073 PSA 50.44000 LogP 2.88 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.546 InChIKey CCKWMCUOHJAVOL-UHFFFAOYSA-N SMILES O=c1cc(C(F)(F)F)c2ccc(O)cc2o1 Water Solubility DMF: soluble |
| Use of | 4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1]. Properties Articles17 Name 7-Hydroxy-4-(trifluoromethyl)coumarin Synonym More Synonyms 7-Hydroxy-4-(trifluoromethyl)coumarin Biological Activity Description 4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Others References [1]. Renwick AB, et, al. Evaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymes. Xenobiotica. 2001 Dec;31(12):861-78. Chemical & Physical Properties Molecular Formula C10H5F3O3 Exact Mass 230.019073 PSA 50.44000 Index of Refraction 1.546 InChIKey CCKWMCUOHJAVOL-UHFFFAOYSA-N Water Solubility DMF: soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (4-Trifluoromethylumbelliferone) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (4-Trifluoromethylumbelliferone) International air transport hazard regulations: Toxic solid, organic, n.o.s. (4-Trifluoromethylumbelliferone) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available See reverse side of invoice or packing slip. |
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