![1H-pyrazolo[3,4-d]pyrimidine-4,6-diol structure, CAS 2465-59-0](/structures/80000/69380_1_2465_59_0.png)
CAS Number2465-59-0
SynonymsOXYPURINOL; BW-55-5; Alloxanthine; OXIPURINOL; 1H-pyrazolo[3,4-d]pyrimidine-4,6-diol; 4,6-Dihydropyrazolo Pyrimidine; MFCD00056934; 1,7-Dihydro; 4,6-DIHYDROXYPYRAZOLO[3,4-D]PYRIMIDINE; 4,6-Dihydroxy-1H-pyrazolo[3,4-d]pyrimidine; EINECS 219-570-9; Oxyprim; Oxoallopurinol
Molecular FormulaC5H4N4O2
Molecular Weight152.11
Purity≥98 (HPLC)%
Density2.19g/cm3
Boiling Point662.9ºC at 760 mmHg
Melting Point300 °C
Appearancepowder
EINECS219-570-9
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2465-59-0 |
| Catalog No. | 2A-9069380 |
| Chinese Name | 4,6-二羟基吡唑啉[3,4-d]嘧啶 |
| Synonyms | OXYPURINOL; BW-55-5; Alloxanthine; OXIPURINOL; 1H-pyrazolo[3,4-d]pyrimidine-4,6-diol; 4,6-Dihydropyrazolo Pyrimidine; MFCD00056934; 1,7-Dihydro; 4,6-DIHYDROXYPYRAZOLO[3,4-D]PYRIMIDINE; 4,6-Dihydroxy-1H-pyrazolo[3,4-d]pyrimidine; EINECS 219-570-9; Oxyprim; Oxoallopurinol |
| Molecular Formula | C5H4N4O2 |
| Molecular Weight | 152.11 |
| Purity | ≥98 (HPLC) |
| Density | 2.19g/cm3 |
| Boiling Point | 662.9ºC at 760 mmHg |
| Melting Point | 300 °C |
| Appearance | powder |
| Storage Condition | Keep container sealed, placed in a tight-fitting c |
| Application | Oxopurinol (Oxipurinol) is the main active metabolite of Allopurinol and is a xanthine oxidase inhibitor. Oxipurinol can be used to regulate blood uric acid levels and treat gout. |
| EINECS | 219-570-9 |
| HTC | 2933990090 |
| PubChem ID | 24898041 |
| MDL Number | MFCD00056934 |
| SMILES | O=C1NC(=O)c2cn[nH]c2N1 |
| InChI | 1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11) |
| InChI Key | HXNFUBHNUDHIGC-UHFFFAOYSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| MSDS | msds/69380_1_2465_59_0.pdf |
| Bioactivity | Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout[1]. Related Catalog Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase Target Human Endogenous Metabolite In Vitro Allopurinol is rapidly metabolized (half-life approximately 1 h) to its active metabolite oxypurinol. Oxypurinol is an inhibitor of xanthine oxidoreductase and has a considerably longer elimination half-life (approximately 23 h)[1]. References [1]. Stocker SL, et al. The pharmacokinetics of oxypurinol in people with gout. Br J Clin Pharmacol. 2012 Sep;74(3):477-89. Chemical & Physical Properties Density 2.19g/cm3 Boiling Point 662.9ºC at 760 mmHg Melting Point 300 °C Molecular Formula C5H4N4O2 Molecular Weight 152.11 Flash Point 354.7ºC Exact Mass 152.03300 PSA 94.92000 Vapour Pressure 3.5E-18mmHg at 25°C Index of Refraction 1.989 Storage condition -20°C Freezer |
| Use of | Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout[1]. Properties Articles40 Name alloxanthine Synonym More Synonyms Oxipurinol Biological Activity Description Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout[1]. Related Catalog Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase Human Endogenous Metabolite In Vitro Allopurinol is rapidly metabolized (half-life approximately 1 h) to its active metabolite oxypurinol. Oxypurinol is an inhibitor of xanthine oxidoreductase and has a considerably longer elimination half-life (approximately 23 h)[1]. References [1]. Stocker SL, et al. The pharmacokinetics of oxypurinol in people with gout. Br J Clin Pharmacol. 2012 Sep;74(3):477-89. Chemical & Physical Properties Molecular Formula C5H4N4O2 Exact Mass 152.03300 PSA 94.92000 Index of Refraction 1.989 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Heterocyclic Building Blocks | ||
|---|---|---|
| 1H-indazole-5-carboxylicacid | 561700-61-6 | 2A-9069354 |
| 1H-indazole-6-carbonitrile | 141290-59-7 | 2A-9069357 |
| 1H-indazole-7-carboxylicacid | 755752-82-0 | 2A-9069359 |
| 1H-indole-2-carboxamide | 1670-84-4 | 2A-9069360 |
| 1H-pyrazolo[3,4-c]pyridine | 271-47-6 | 2A-9069379 |
| 1H-pyrazolo[4,3-c]pyridine | 271-52-3 | 2A-9069381 |
| 1H-pyrrole-3-carbonitrile | 7126-38-7 | 2A-9069383 |
| 1H-pyrrolo[3,2-c]pyridine-2-carbaldehyde | 630395-95-8 | 2A-9069391 |
| 1-isopropyl-1H-pyrazole-4-carbaldehyde | 313735-67-0 | 2A-9069392 |
| 1-methyl-1H-indazole-4-carbaldehyde | 1053655-56-3 | 2A-9069399 |
| Browse all Heterocyclic Building Blocks products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS