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Isoquercitrin structure, CAS 482-35-9

Isoquercitrin

CAS Number482-35-9

SynonymsQuercetin 3-O-β-glucoside; trifoliin; quercetin 3-O-β-D-glucopyranoside; Quercetin 3β-O-glucoside; Quercetin 3-β-glucoside; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl β-D-glucopyranoside; Quercetin 3-β-D-glucoside; 3-O-β-D-Glucopyranosylquercetin; Quercetin glucoside; Quercetin-3-O-β-D-glucoside; Quercetin-3-O-β-glucopyranoside; Isoquercetrin; Quercetin 3-O-glucoside; Quercetin 3-D-glucoside; Isoquercitrin; isoquercetin; quercetin 3-O-β-D-glucoside; Hirsutrin; isotrifoliin; Quercetin 3-glucoside; Quercetin-3-β-glucopyranoside; Quercetin-3-O-glucoside; Quercetin 3-β-O-glucoside; Quercetin 3-O-glucopyranoside

Molecular FormulaC21H20O12

Molecular Weight464.38

Purity≥90 (HPLC)%

Density1.9±0.1 g/cm3

Boiling Point872.6±65.0 °C at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9069021 Purity: ≥90 (HPLC)%
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Quality Control of [ 482-35-9 ] Purity: ≥90 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number482-35-9
Catalog No.2A-9069021
Chinese Name异槲皮苷
SynonymsQuercetin 3-O-β-glucoside; trifoliin; quercetin 3-O-β-D-glucopyranoside; Quercetin 3β-O-glucoside; Quercetin 3-β-glucoside; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl β-D-glucopyranoside; Quercetin 3-β-D-glucoside; 3-O-β-D-Glucopyranosylquercetin; Quercetin glucoside; Quercetin-3-O-β-D-glucoside; Quercetin-3-O-β-glucopyranoside; Isoquercetrin; Quercetin 3-O-glucoside; Quercetin 3-D-glucoside; Isoquercitrin; isoquercetin; quercetin 3-O-β-D-glucoside; Hirsutrin; isotrifoliin; Quercetin 3-glucoside; Quercetin-3-β-glucopyranoside; Quercetin-3-O-glucoside; Quercetin 3-β-O-glucoside; Quercetin 3-O-glucopyranoside
Molecular FormulaC21H20O12
Molecular Weight464.38
Purity≥90 (HPLC)
Density1.9±0.1 g/cm3
Boiling Point872.6±65.0 °C at 760 mmHg
Storage Condition−20°C
ApplicationQuercetin-3-glucoside Quercetin-3-glucoside is a naturally occurring polyphenol with antioxidant, anti-proliferative and anti-inflammatory properties. Quercetin-3-glucoside alleviates ethanol-induced
PubChem ID57647673
MDL NumberMFCD00017746
SMILESOC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O
InChI1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1
InChI KeyOVSQVDMCBVZWGM-QSOFNFLRSA-N
Beilstein/REAXYS100989
NACRES CodeNA.25
UNSPSC12352205
Hazard Symbolstransportation
MSDSmsds/69021_1_482_35_9.pdf
BioactivityQuercetin-3-glucoside is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties.Quercetin-3-glucoside alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway[1].Quercetin-3-glucoside regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Quercetin-3-glucoside has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies[2]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology In Vitro Quercetin-3-glucoside (5-20 μM; 24 hours) substantially reduces ethanol-induced cytotoxicity , protects hepatic cells against ethanol‐stimulated liver injury[1].Quercetin-3-glucoside (10 μM; pre-treat 1 hour) dramatically downregulates the levels of ethanol-induced iNOS protein expression in HepG2 cells[1]. Cell Viability Assay[1] Cell Line: HepG2 cells Concentration: 5 μM, 10 μM, 20 μM Incubation Time: 24 hours Result: Caused significantly enhanced cell viability as positive controls. Western Blot Analysis[1] Cell Line: HepG2 cells Concentration: 10 μM Incubation Time: 1 hour Result: Decreased ethanol‐ induced iNOS protein expression. References [1]. Lee S, et al. Relative protective activities of quercetin, quercetin-3-glucoside, and rutin in alcohol-induced liver injury. J Food Biochem. 2019 Aug 5:e13002. [2]. Tan C, et al. Modulation of nuclear factor-κB signaling and reduction of neural tube defects by quercetin-3-glucoside in embryos of diabetic mice. Am J Obstet Gynecol. 2018 Aug;219(2):197.e1-197.e8. Chemical & Physical Properties Density 1.9±0.1 g/cm3 Boiling Point 872.6±65.0 °C at 760 mmHg Molecular Formula C21H20O12 Molecular Weight 464.376 Flash Point 307.5±27.8 °C Exact Mass 464.095490 PSA 210.51000 LogP 1.75 Vapour Pressure 0.0±0.3 mmHg at 25°C Index of Refraction 1.803 InChIKey OVSQVDMCBVZWGM-QSOFNFLRSA-N SMILES O=c1c(OC2OC(CO)C(O)C(O)C2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 Storage condition −20°C
Use ofProperties Articles55 Name 3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin, Quercetin 3-β-D-glucoside Synonym More Synonyms Isoquercitrin Biological Activity Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology References [1]. Lee S, et al. Relative protective activities of quercetin, quercetin-3-glucoside, and rutin in alcohol-induced liver injury. J Food Biochem. 2019 Aug 5:e13002. [2]. Tan C, et al. Modulation of nuclear factor-κB signaling and reduction of neural tube defects by quercetin-3-glucoside in embryos of diabetic mice. Am J Obstet Gynecol. 2018 Aug;219(2):197.e1-197.e8. Chemical & Physical Properties Molecular Formula C21H20O12 Exact Mass 464.095490 PSA 210.51000 Index of Refraction 1.803 InChIKey OVSQVDMCBVZWGM-QSOFNFLRSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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