![4-(7-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)benzonitrile structure, CAS 105365-76-2](/structures/80000/68494_1_105365_76_2.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 105365-76-2 |
| Catalog No. | 2A-9068494 |
| Chinese Name | RS 8359 |
| Synonyms | 4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]benzonitrile; UNII:79U9T1HIX9; RS 8359 |
| Molecular Formula | C14H12N4O |
| Molecular Weight | 252.28 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 483.6±45.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | RS 8359 is a selective, reversible MAO-A inhibitor with antidepressant efficacy. |
| HTC | 2933990090 |
| MDL Number | C14H12N4O |
| SMILES | N#Cc1ccc(Nc2ncnc3c2CCC3O)cc1 |
| InChI Key | YKTSVZRWKHWINV-UHFFFAOYSA-N |
| MSDS | msds/68494_1_105365_76_2.pdf |
| Use of | RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity. Properties Name 4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]be nzonitrile Synonym More Synonyms RS 8359 Biological Activity Description RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity. Related Catalog Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease In Vivo RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine. RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect[1]. References [1]. Iwata N, et al. Pharmacology of the new reversible inhibitor of monoamine oxidase A, RS-8359. Int Clin Psychopharmacol. 1997 Sep;12 Suppl 5:S3-10. Chemical & Physical Properties Molecular Formula C14H12N4O Exact Mass 252.101105 PSA 81.83000 Index of Refraction 1.682 InChIKey YKTSVZRWKHWINV-UHFFFAOYSA-N Storage condition 2-8℃ Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 5-(4-chlorobenzylsulfonyl)-1,3,4-thiadiazol-2-amine | 880791-53-7 | 2A-9068432 |
| 5-(butylsulfonyl)-1,3,4-thiadiazol-2-amine | 72836-17-0 | 2A-9068433 |
| 4-(5-bromothiophen-2-ylsulfonyl)tetrahydro-2H-pyran | 1253790-83-8 | 2A-9068436 |
| 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone | 34773-51-8 | 2A-9068437 |
| (1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)methanamine | 199014-16-9 | 2A-9068442 |
| 3-Amino-2-chloroisonicotinamide | 342899-34-7 | 2A-9068496 |
| Methyl3-amino-2-chloroisonicotinate | 173435-41-1 | 2A-9068497 |
| methyl-2-amino-2-cyclopropylacetatehydrochloride | 535936-86-8 | 2A-9068513 |
| 2-amino-2-cyclopropylaceticacidhydrochloride | 1219429-81-8 | 2A-9068516 |
| 3-(4-methoxyphenyl)propan-1-ol | 5406-18-8 | 2A-9068519 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS