CAS Number35604-67-2
SynonymsEmovit; Viloxacina clorhidrato [Spanish]; EINECS 252-638-6; Viloxazine HCl; Viloxazine hydrochloride; Vivalan; 2-[(2-Ethoxyphenoxy)-methyl]morpholine hydrochloride; Vicilan
Molecular FormulaC13H20ClNO3
Molecular Weight273.76
Purity≥95 (HPLC)%
Density1.061g/cm3
Boiling Point350.5ºC at 760mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 35604-67-2 |
| Catalog No. | 2A-9068256 |
| Chinese Name | 2-[(2-乙氧基苯氧基)甲基]吗啉盐酸盐 |
| Synonyms | Emovit; Viloxacina clorhidrato [Spanish]; EINECS 252-638-6; Viloxazine HCl; Viloxazine hydrochloride; Vivalan; 2-[(2-Ethoxyphenoxy)-methyl]morpholine hydrochloride; Vicilan |
| Molecular Formula | C13H20ClNO3 |
| Molecular Weight | 273.76 |
| Purity | ≥95 (HPLC) |
| Density | 1.061g/cm3 |
| Boiling Point | 350.5ºC at 760mmHg |
| Appearance | powder |
| Application | Viloxazine hydrochloride is the inactive isomer of Viloxazine (HY-W380450) and can be used as a control compound in experiments. Viloxazine (Viloxazin) is a norepinephrine reuptake inhibitor and a pot |
| HTC | 2934999090 |
| MDL Number | MFCD00661100 |
| SMILES | CCOC1=C(OCC2OCCNC2)C=CC=C1.Cl |
| InChI | 1S/C13H19NO3.ClH/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11;/h3-6,11,14H,2,7-10H2,1H3;1H |
| InChI Key | HJOCKFVCMLCPTP-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/68256_1_35604_67_2.pdf |
| Use of | Properties Name 2-[(2-ethoxyphenoxy)methyl]morpholine,hydrochloride Synonym More Synonyms Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Yu C, et al. New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties. J Exp Pharmacol. 2020 Aug 25;12:285-300. [2]. Pinder RM, et al. Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1977 Jun;13(6):401-21. Chemical & Physical Properties Exact Mass 273.11300 PSA 39.72000 LogP 2.58330 InChIKey HJOCKFVCMLCPTP-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Morpholine, 2-((2-ethoxyphenoxy)methyl)-, hydrochloride CAS REGISTRY NUMBER : 35604-67-2 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T6M DOTJ C1OR BO2 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : DOSE/DURATION : TOXIC EFFECTS : Behavioral - hallucinations, distorted perceptions Behavioral - convulsions or effect on seizure threshold REFERENCE : BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 2,96,1977 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Human - woman DOSE/DURATION : TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - sleep REFERENCE : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,812,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 22,385,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 35,812,1980 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : Safety Information HS Code 2934999090 Precursor & DownStream Precursor 2 CAS#:94-71-3 2-Ethoxyphenol CAS#:5296-35-5 2-[(2-ethoxyphe... DownStream 1 CAS#:46817-91-8 2-[(2-ethoxyphe... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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