CAS Number57498-96-1
SynonymsCarpachromene; Carpachromen; Flemichin B; 2S-Lupinifolin; 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chromen-6-one
Molecular FormulaC20H16O5
Molecular Weight336.34
Density1.4±0.1 g/cm3
Boiling Point562.1±50.0 °C at 760 mmHg
Appearanceyellow powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 57498-96-1 |
| Catalog No. | 2A-9067409 |
| Chinese Name | 5-羟基-8-(4-羟基苯基)-2,2-二甲基-2H,6H-苯并[1,2-b:5,4-b']二吡喃-6-酮 |
| Synonyms | Carpachromene; Carpachromen; Flemichin B; 2S-Lupinifolin; 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chromen-6-one |
| Molecular Formula | C20H16O5 |
| Molecular Weight | 336.34 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 562.1±50.0 °C at 760 mmHg |
| Appearance | yellow powder |
| Storage Condition | ?20°C |
| Application | Carpachromene is a potent alpha-glucosidase inhibitor. Carpachromene improves insulin resistance in HepG2 cells by regulating the IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway [1]. |
| SMILES | CC1(C)C=Cc2c(cc3oc(-c4ccc(O)cc4)cc(=O)c3c2O)O1 |
| InChI Key | YXOATFKTEDZPFL-UHFFFAOYSA-N |
| Hazard Symbols | 50 |
| MSDS | msds/67409_2_57498_96_1.pdf |
| Bioactivity | Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1]. Related Catalog Research Areas >> Cancer References [1]. Alaaeldin R, et al. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021 Dec 16;26(24):7629. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 562.1±50.0 °C at 760 mmHg Molecular Formula C20H16O5 Molecular Weight 336.34 Flash Point 205.8±23.6 °C Exact Mass 336.099762 PSA 79.90000 LogP 4.60 Vapour Pressure 0.0±1.6 mmHg at 25°C Index of Refraction 1.660 InChIKey YXOATFKTEDZPFL-UHFFFAOYSA-N SMILES CC1(C)C=Cc2c(cc3oc(-c4ccc(O)cc4)cc(=O)c3c2O)O1 Storage condition ?20°C |
| Use of | Properties Name 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chr omen-6-one Synonym More Synonyms Carpachromene Biological Activity Related Catalog Research Areas >> Cancer References Chemical & Physical Properties Molecular Formula C20H16O5 Exact Mass 336.099762 PSA 79.90000 Index of Refraction 1.660 InChIKey YXOATFKTEDZPFL-UHFFFAOYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3077 International Maritime Transport Danger Regulations: 3077 International Air Transport Danger Regulations: 3077 14.2 United Nations shipping name European land transport hazard regulations: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Carpachromene) IMDG Code: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Carpachromene) International air transport hazard regulations: Environmentally hazardous substance, solid, n.o.s. (Carpachromene) 14.3 Transport hazard categories European land transport Dangerous Regulations: 9 International sea transport Dangerous Regulations: 9 International air transport Dangerous Regulations: 9 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: Yes International Maritime Transport Dangerous Regulations International Air Transport Dangerous Regulations: Yes Marine Pollutants (Yes/No): Yes 14.6 Special reminder to users further information Dangerous goods are individually packaged, with liquids exceeding 5 liters or solids exceeding 5 kilograms. The outer packaging of each independent package and the combined independent inner package must have EHS on it. Identification (according to European ADR Regulation 2.2.9.1.10, IMDG Regulation 2.10.3), |
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