CAS Number17306-46-6
SynonymsApigenin-7-O-neohesperidoside; Apigenin-7-neohesperidoside; RHOIFOLOSIDE; Apigenin 7-O-neo-hesperidoside; apigenin 7-O-neohesperidoside; Rhoifolin; Apigenin-7-rhamnoglucoside
Molecular FormulaC27H30O14
Molecular Weight578.52
Purity≥95.0 (HPLC)%
Density1.7±0.1 g/cm3
Boiling Point916.5±65.0 °C at 760 mmHg
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 17306-46-6 |
| Catalog No. | 2A-9067233 |
| Chinese Name | 野漆树苷 |
| Synonyms | Apigenin-7-O-neohesperidoside; Apigenin-7-neohesperidoside; RHOIFOLOSIDE; Apigenin 7-O-neo-hesperidoside; apigenin 7-O-neohesperidoside; Rhoifolin; Apigenin-7-rhamnoglucoside |
| Molecular Formula | C27H30O14 |
| Molecular Weight | 578.52 |
| Purity | ≥95.0 (HPLC) |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 916.5±65.0 °C at 760 mmHg |
| Storage Condition | 0-6°C |
| Application | Rhoifolin is a flavonoid glycoside isolated from Citrus grandis leaves. Rhoifolin benefits diabetic complications by enhancing adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and |
| MDL Number | MFCD00016773 |
| SMILES | C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C=C(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O |
| InChI | 1S/C27H30O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-8,10,18,20-30,32-36H,9H2,1H3/t10-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1 |
| InChI Key | RPMNUQRUHXIGHK-PYXJVEIZSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/67233_1_17306_46_6.pdf |
| Bioactivity | Rhoifolin is a flavone glycoside isolated from Citrus grandis (L.) Osbeck leaves. Rhoifolin is beneficial for diabetic complications through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation[1]. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways[2]. Related Catalog Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Metabolic Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor Target NF-κB insulin receptor-β MAPK References [1]. Rao YK, et al. Insulin-Mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells. Evid Based Complement Alternat Med. 2011;2011:624375. [2]. Liao S, et al. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. J Cell Physiol. 2019 Aug;234(10):17600-17611. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 916.5±65.0 °C at 760 mmHg Molecular Formula C27H30O14 Molecular Weight 578.519 Flash Point 305.4±27.8 °C Exact Mass 578.163574 PSA 228.97000 LogP 1.72 Vapour Pressure 0.0±0.3 mmHg at 25°C Index of Refraction 1.726 InChIKey RPMNUQRUHXIGHK-PYXJVEIZSA-N SMILES CC1OC(OC2C(Oc3cc(O)c4c(=O)cc(-c5ccc(O)cc5)oc4c3)OC(CO)C(O)C2O)C(O)C(O)C1O Storage condition 0-6°C |
| Use of | Rhoifolin is a flavone glycoside isolated from Citrus grandis (L.) Osbeck leaves. Rhoifolin is beneficial for diabetic complications through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation[1]. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways[2]. Properties Name apigenin 7-O-neohesperidoside Synonym More Synonyms Rhoifolin Biological Activity Description Rhoifolin is a flavone glycoside isolated from Citrus grandis (L.) Osbeck leaves. Rhoifolin is beneficial for diabetic complications through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation[1]. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways[2]. Related Catalog Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Metabolic Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor insulin receptor-β References [2]. Liao S, et al. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. J Cell Physiol. 2019 Aug;234(10):17600-17611. Chemical & Physical Properties Molecular Formula C27H30O14 Exact Mass 578.163574 PSA 228.97000 Index of Refraction 1.726 InChIKey RPMNUQRUHXIGHK-PYXJVEIZSA-N |
| Transport Info | Product Name: Anacardiin |
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